儿童基底动脉闭塞：5例报告及文献复习
Childhood basilar artery occlusion: a report of 5 cases and review of the literature.
作者信息
Chikkannaiah Mahesh, Lo Warren D
机构信息
1Department of Neurology, Nationwide Children's Hospital, Columbus, OH, USA.
出版信息
J Child Neurol. 2014 May;29(5):633-45. doi: 10.1177/0883073813488826. Epub 2013 May 13.
Basilar artery occlusion has poor outcome in adults; little is known regarding outcomes in children. Whether intra-arterial treatments improve adult outcomes is controversial. Safety and efficacy of intra-arterial treatments in children are unknown. We report 5 cases of basilar artery occlusion and review published cases. We estimated National Institute of Health Stroke Scale (NIHSS) and modified Rankin Score (mRS) of published cases, compared scores between non-intra-arterial treatments and intra-arterial treatments groups, and examined the correlation between NIHSS and mRS. Of our cases, 4 had good outcomes and 1 died. Of 63 published cases, 45 had no intra-arterial treatments and 18 had intra-arterial treatments. In the non-intra-arterial treatments group 24 had good outcomes. In the intra-arterial treatments group 13 had good outcomes. There was strong correlation between the NIHSS and the mRS. Children with basilar artery occlusion have better outcomes than adults. Certain children with basilar artery occlusion may be treated conservatively. A registry for childhood basilar artery occlusion is urgently needed.
基底动脉闭塞在成人中预后较差；关于儿童的预后情况所知甚少。动脉内治疗是否能改善成人的预后存在争议。动脉内治疗在儿童中的安全性和有效性尚不清楚。我们报告了5例基底动脉闭塞病例，并回顾了已发表的病例。我们估算了已发表病例的美国国立卫生研究院卒中量表（NIHSS）和改良Rankin量表（mRS），比较了非动脉内治疗组和动脉内治疗组的评分，并研究了NIHSS和mRS之间的相关性。在我们的病例中，4例预后良好，1例死亡。在63例已发表的病例中，45例未接受动脉内治疗，18例接受了动脉内治疗。在非动脉内治疗组中，24例预后良好。在动脉内治疗组中，13例预后良好。NIHSS和mRS之间存在很强的相关性。基底动脉闭塞的儿童比成人预后更好。某些基底动脉闭塞的儿童可以采取保守治疗。迫切需要建立一个儿童基底动脉闭塞登记处。
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