Université de Montréal, CHU Sainte Justine Research Center, 3175, Côte-Sainte-Catherine, Montreal, Quebec, Canada H3T 1C5.
Arch Dis Child Fetal Neonatal Ed. 2012 Sep;97(5):F329-34. doi: 10.1136/fetalneonatal-2011-300969.
To compare late-preterm infants (33-36 weeks) with term infants (≥37 weeks) on incidence of morbidities in the first 3 years of life and healthcare costs during the first 2 years of life and third year of life.
Administrative health records of live infants born between January 1, 1997, and December 31, 2000 with 3 years follow-up data (N=35733) were linked. First, diagnoses of morbidities were compared between late-preterm and term infants using Cox's proportional hazards models. Healthcare costs expressed as mean total costs and cost ratios, accrued following initial hospital discharge after birth, were also examined.
The three most common reasons for hospitalisation in late-preterm and term infants were acute bronchitis, otitis media and pneumonia. The most frequent reasons for physician visits included acute upper respiratory infections, otitis media and bronchiolitis. The highest HR were detected for chronic bronchitis 1.64 (1.13-2.39), hearing loss 1.56 (1.14-2.15) and bacterial diseases 1.28 (1.09-1.49). The mean total cost for late-preterm infants during the first 2 years of life was $2568 CAD compared with $1285 CAD for term infants, cost ratio =1.99 (95% CI 1.90 to 2.09). In the third year of life, the cost ratio reduced to 1.46 (95% CI 1.39 to 1.54).
Late-preterm infants are at higher risk of specific morbidities compared with term infants. Their mean total costs fall from almost double that of term infants during the first 2 years of life, to just 46% greater in the third year of life.
比较早产儿（33-36 周）与足月儿（≥37 周）在生命最初 3 年的发病情况以及生命最初 2 年和第 3 年的医疗保健费用。
对 1997 年 1 月 1 日至 2000 年 12 月 31 日期间出生并随访 3 年（n=35733）的活产婴儿的行政健康记录进行了链接。首先，使用 Cox 比例风险模型比较了早产儿和足月儿的发病情况。还检查了出生后最初住院出院后以平均总费用和费用比表示的医疗保健费用。
早产儿和足月儿住院的最常见原因是急性支气管炎、中耳炎和肺炎。就诊最常见的原因包括急性上呼吸道感染、中耳炎和细支气管炎。慢性支气管炎的最高 HR 为 1.64（1.13-2.39）、听力损失为 1.56（1.14-2.15）、细菌性疾病为 1.28（1.09-1.49）。早产儿生命最初 2 年的平均总费用为 2568 加元，而足月儿为 1285 加元，费用比=1.99（95%CI 1.90-2.09）。在生命的第 3 年，费用比降低至 1.46（95%CI 1.39-1.54）。
与足月儿相比，早产儿发生特定疾病的风险更高。他们的平均总费用从生命最初 2 年几乎是足月儿的两倍，下降到第 3 年仅增加 46%。
