Pereţianu D, Balmeş E, Gudovan E, Ursu H I, Oprescu S, Ilinca D
Department of Endocrinology and Applied Immunology, Hospital of The 4th District, Bucharest, Romania.
Endocrinologie. 1990 Apr-Jun;28(2):63-6.
HLA B 35 antigen was assessed in 19 patients with viral subacute thyroiditis. The antigen was present in 68.43% of patients (no = 13). The relative risk (vs 500 health blood donors) is very high (12.27), with X2 = 33.4 and p less than 0.001. Despite the high relative risk, the presence/absence of HLA B 35 antigen showed no correlations with the main clinical features in our patients; no correlations can be made for: erythrocyte sedimentation rate, radioiodine uptake, thyromegaly, hyperthyroidism and evolution.
对19例亚急性病毒性甲状腺炎患者进行了HLA B 35抗原检测。68.43%的患者(n = 13)存在该抗原。相对风险(与500名健康献血者相比)非常高(12.27),X2 = 33.4,p < 0.001。尽管相对风险很高,但在我们的患者中,HLA B 35抗原的存在与否与主要临床特征无相关性;在以下方面无法建立相关性:红细胞沉降率、放射性碘摄取、甲状腺肿大、甲状腺功能亢进及病情演变。