Mottard S, Grimer R J, Abudu A, Carter S R, Tillman R M, Jeys L, Spooner D
Maisonneuve-Rosemont Hospital, Montreal H1T 4B3, Canada.
J Bone Joint Surg Br. 2012 Sep;94(9):1282-7. doi: 10.1302/0301-620X.94B9.29164.
The purpose of this study was to assess the outcome of 15 patients (mean age 13.6 years (7 to 25)) with a primary sarcoma of the tibial diaphysis who had undergone excision of the affected segment that was then irradiated (90 Gy) and reimplanted with an ipsilateral vascularised fibular graft within it. The mean follow-up was 57 months (22 to 99). The mean time to full weight-bearing was 23 weeks (9 to 57) and to complete radiological union 42.1 weeks (33 to 55). Of the 15 patients, seven required a further operation, four to obtain skin cover. The mean Musculoskeletal Society Tumor Society functional score at final follow-up was 27 out of 30 once union was complete. The functional results were comparable with those of allograft reconstruction and had a similar rate of complication. We believe this to be a satisfactory method of biological reconstruction of the tibial diaphysis in selected patients.
本研究的目的是评估15例(平均年龄13.6岁(7至25岁))原发性胫骨干肉瘤患者的治疗结果,这些患者接受了受累节段切除,随后进行放疗(90 Gy),并在其中植入同侧带血管腓骨移植骨。平均随访时间为57个月(22至99个月)。完全负重的平均时间为23周(9至57周),放射学完全愈合的平均时间为42.1周(33至55周)。15例患者中,7例需要再次手术,4例是为了获得皮肤覆盖。最终随访时,一旦达到愈合,肌肉骨骼学会肿瘤学会功能评分平均为30分中的27分。功能结果与同种异体骨重建相当,并发症发生率相似。我们认为这是在特定患者中对胫骨干进行生物重建的一种令人满意的方法。