Khanna Reena, Shen Bo
Department of Gastroenterology and Hepatology, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Gastroenterol Hepatol (N Y). 2012 May;8(5):322-6.
Ileal pouch-anal anastomosis (IPAA) following total proctocolectomy has become the surgical treatment of choice for ulcerative colitis patients who have medically refractory disease or neoplasia. Unfortunately, various metabolic complications have been reported with this surgical procedure, including anemia, vitamin B(12) deficiency, bile salt and fat malabsorption, vitamin D deficiency, bone loss, and nephrolithiasis. Recognition and early diagnosis of these complications are important when managing IPAA patients.
全直肠结肠切除术后回肠储袋肛管吻合术(IPAA)已成为患有药物难治性疾病或肿瘤的溃疡性结肠炎患者的手术治疗选择。不幸的是,该手术已报告了各种代谢并发症,包括贫血、维生素B12缺乏、胆盐和脂肪吸收不良、维生素D缺乏、骨质流失和肾结石。在管理IPAA患者时,认识并早期诊断这些并发症很重要。