The adaptive response (drug tolerance) helps to prevent drug-induced liver injury.
作者信息
Lewis James H
机构信息
Hepatology Division of Gastroenterology, Department of Medicine, Georgetown University Hospital, Washington, DC, USA.
出版信息
Gastroenterol Hepatol (N Y). 2012 May;8(5):333-6.
Abstract
摘要
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Liver function tests and statins.肝功能检查与他汀类药物
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2
Drug-induced acute liver failure: results of a U.S. multicenter, prospective study.药物性急性肝衰竭：美国多中心前瞻性研究结果。
Hepatology. 2010 Dec;52(6):2065-76. doi: 10.1002/hep.23937. Epub 2010 Oct 14.
3
Predicting and preventing acute drug-induced liver injury: what's new in 2010?预测和预防急性药物性肝损伤：2010 年有哪些新进展？
Expert Opin Drug Metab Toxicol. 2010 Sep;6(9):1047-61. doi: 10.1517/17425255.2010.503706.
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Mechanisms of pathogenesis in drug hepatotoxicity putting the stress on mitochondria.药物性肝毒性的发病机制：聚焦于线粒体
Mol Interv. 2010 Apr;10(2):98-111. doi: 10.1124/mi.10.2.7.
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Mechanisms of immune-mediated liver injury.免疫介导的肝损伤机制。
Toxicol Sci. 2010 Jun;115(2):307-21. doi: 10.1093/toxsci/kfq009. Epub 2010 Jan 13.
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Causes, clinical features, and outcomes from a prospective study of drug-induced liver injury in the United States.美国药物性肝损伤前瞻性研究的病因、临床特征及结果
Gastroenterology. 2008 Dec;135(6):1924-34, 1934.e1-4. doi: 10.1053/j.gastro.2008.09.011. Epub 2008 Sep 17.
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Role of IL-6 in an IL-10 and IL-4 double knockout mouse model uniquely susceptible to acetaminophen-induced liver injury.白细胞介素-6在对乙酰氨基酚诱导的肝损伤具有独特易感性的白细胞介素-10和白细胞介素-4双敲除小鼠模型中的作用。
Chem Res Toxicol. 2007 Feb;20(2):208-16. doi: 10.1021/tx060228l.
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Drug-related hepatotoxicity.药物相关性肝毒性。
N Engl J Med. 2006 Feb 16;354(7):731-9. doi: 10.1056/NEJMra052270.
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'Hy's law,' the 'Rezulin Rule,' and other predictors of severe drug-induced hepatotoxicity: putting risk-benefit into perspective.“海氏法则”、“曲格列酮规则”及其他严重药物性肝毒性的预测指标：权衡风险与获益
Pharmacoepidemiol Drug Saf. 2006 Apr;15(4):221-9. doi: 10.1002/pds.1209.
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Idiosyncratic drug hepatotoxicity.特异质性药物肝毒性
Nat Rev Drug Discov. 2005 Jun;4(6):489-99. doi: 10.1038/nrd1750.
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