Institute of Oncology Ljubljana, Ljubljana, Slovenia.
Radiol Oncol. 2010 Sep;44(3):135-41. doi: 10.2478/v10019-010-0018-8. Epub 2010 Sep 9.
Though the post treatment surveillance of patients with colorectal cancer (CRC) treated with curative intent is common practice, its value is controversial. In the absence of conclusive clinical data, various modalities for the routine follow-up of patients with CRC have been proposed. In practice, the guidelines across countries and regions differ and are influenced by different health care policies, resource availability and doubts about effectiveness of follow-up.
The results of metaanalyses of available clinical trials demonstrated a survival benefit of intensified monitoring, but the questions regarding the optimal frequency of visits and the examinations to be performed remain unanswered. Furthermore, intensive monitoring of CRC survivors may be difficult to be administrated, causes discomfort and morbidity to the patient and can have serious cost-implications to the healthcare system. However, as it seems from available data, a comprehensive surveillance program does not affect the quality of patients' life. Ongoing large prospective multi-institutional randomised trials might elucidate some of the crucial questions and existing dilemmas to establish adequate surveillance strategy for CRC patients.
尽管对接受根治性治疗的结直肠癌（CRC）患者进行治疗后监测是常见做法，但其实用价值仍存在争议。在缺乏确凿临床数据的情况下，人们提出了各种 CRC 患者常规随访的方法。在实践中，不同国家和地区的指南不同，受到不同的医疗保健政策、资源可用性以及对随访效果的怀疑的影响。
对现有临床试验的荟萃分析结果表明，强化监测具有生存获益，但关于最佳随访频率和要进行的检查仍存在疑问。此外，对 CRC 幸存者的密集监测可能难以管理，会给患者带来不适和发病，并且会对医疗保健系统造成严重的成本影响。然而，从现有数据来看，综合监测方案似乎不会影响患者的生活质量。正在进行的大型前瞻性多机构随机试验可能会阐明一些关键问题和现有困境，从而为 CRC 患者建立适当的监测策略。
