Department of Surgery, Izmir Bozyaka Training and Research Hospital, Izmir, Turkey.
Radiol Oncol. 2011 Jun;45(2):129-31. doi: 10.2478/v10019-010-0053-5. Epub 2010 Dec 31.
Brunner's gland adenoma (BGA) is a rare benign duodenal tumour proliferating from Brunner's glands. Here, we present a giant BGA leading to anaemia, with its clinical, endoscopic, radiological, surgical and pathological findings.
A 48-year-old Turkish man complained of a six months history of vague epigastric discomfort, loss of appetite and nausea after meals without vomiting. The physical examination had no unremarkable finding. Laboratory findings, including liver function tests, were within normal limits except a hypochromic, microcytic anaemia. The upper gastrointestinal endoscopic examination revealed a lobulated, red, polypoid tumour with a smooth surface covered with normal mucosa. The tumour was located on the anterior surface of duodenal bulb and had a wide base measuring 3.5 × 4 cm in size. Endoscopic ultrasonography revealed a submucosal polypoid mass located at the anterior surface of duodenal bulb. The endoscopic excision was tried but was not successful. The patient was operated and transduodenal polypectomy was done. The postoperative period was uneventful and the pathologic diagnosis was assessed as Brunner's gland adenoma. During the follow-up period, the endoscopic examination was normal at 12th month postoperatively.
BGA is a rare benign cause of anaemia that can be treated with excellent results.
布伦纳氏腺腺瘤（BGA）是一种罕见的良性十二指肠肿瘤，由布伦纳氏腺增生引起。本文报道了一例导致贫血的巨大 BGA，包括其临床表现、内镜、影像学、手术和病理特征。
一名 48 岁的土耳其男性，因上腹不适、食欲减退和餐后恶心（无呕吐）6 个月来就诊。体格检查无明显异常。实验室检查除小细胞低色素性贫血外，其余肝功能检查均正常。上消化道内镜检查发现十二指肠球部有一个分叶状、红色、息肉样肿瘤，表面光滑，覆盖正常黏膜。肿瘤位于十二指肠球部前壁，基底较宽，大小为 3.5×4cm。内镜超声检查显示十二指肠球部前壁黏膜下有一个息肉样肿块。尝试内镜切除，但未成功。患者接受了手术，行经十二指肠息肉切除术。术后恢复顺利，病理诊断为布伦纳氏腺腺瘤。术后 12 个月的内镜随访正常。
BGA 是一种罕见的良性贫血病因，治疗效果良好。
