East TN State University, Quillen College of Medicine, Johnson City, Tennessee, USA.
Radiol Oncol. 2012 Mar;46(1):23-7. doi: 10.2478/v10019-011-0032-5. Epub 2011 Oct 8.
For years, the treatment for invasive lobular carcinoma (ILC) has been mastectomy secondary to the lack of studies investigating the efficacy of breast conservation therapy on patients afflicted with ILC and due to the lack of long-term follow up investigating locoregional recurrence in this patient population. In this article we report the clinical course of a patient diagnosed with ILC.
We describe the case of a 50-year-old woman with stage IIB (T2N1M0) ER/PR positive right breast ILC who underwent a right modified radical mastectomy, postoperative chemotherapy, a prophylactic left simple mastectomy with bilateral breast reconstruction and tamoxifen. Approximately 12 years later, she presented with a deflated breast implant and recurrent breast cancer with metastatic spread. She received palliative radiotherapy then palliative chemotherapy. Unfortunately, she succumbed to the cancer less than a year after being diagnosed with metastatic disease.
This may be the first case report of a ruptured breast implant presenting at the same time as the diagnosis of recurrent breast cancer.
多年来,由于缺乏研究调查保乳治疗对浸润性小叶癌(ILC)患者的疗效,以及缺乏针对该患者人群局部区域复发的长期随访研究,浸润性小叶癌的治疗一直是乳房切除术。在本文中,我们报告了一名诊断为 ILC 的患者的临床过程。
我们描述了一名 50 岁女性的病例,她患有 IIB 期(T2N1M0)ER/PR 阳性右乳 ILC,接受了右改良根治性乳房切除术、术后化疗、预防性左单纯乳房切除术和双侧乳房重建以及他莫昔芬治疗。大约 12 年后,她出现了乳房植入物瘪陷和复发性乳腺癌伴转移。她接受了姑息性放疗和姑息性化疗。不幸的是,她在诊断为转移性疾病不到一年后就死于癌症。
这可能是首例破裂乳房植入物与复发性乳腺癌同时诊断的病例报告。