[标准化屋尘螨变应原制剂特异性免疫治疗过敏性鼻炎的疗效评估]
[Efficacy evaluation of specific immunotherapy with standardized house dust mite allergen preparation for allergic rhinitis].
作者信息
Zhou Jie, He Yuanping, Zeng Xudong, Li Zewen, Pan Fangming, Chen Yingchao, Li Zhaolong
机构信息
Department of Otolaryngology, the Central of Xiaogan Hospital, Huazhong University of Science and Technology, Wuhan, 432000, China.
出版信息
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2012 Jun;26(11):487-9.
OBJECTIVE
To evaluate the efficacy of specific immunotherapy (SIT) with standardized house dust mite allergen preparation for allergic rhinitis (AR).
METHOD
Fifty-five patients with allergic rhinitis caused by house dust mites were selected in this self-control study. Clinical efficacy was evaluated by symptom and sign score after two years of specific immunotherapy and compared with pre-treatment scores.
RESULT
After completing the study, a clinically significant reduction in symptom and sign score in these patients was noted, compared with that of pretreatment. And the difference was statistically significant (P < 0.01).
CONCLUSION
Standardized house dust mite allergen preparation is an effective treatment in patients suffering from allergic rhinitis due to house dust mites.
目的
评估标准化屋尘螨变应原制剂特异性免疫疗法（SIT）治疗变应性鼻炎（AR）的疗效。
方法
本自身对照研究选取了55例由屋尘螨引起的变应性鼻炎患者。经过两年特异性免疫疗法后，通过症状和体征评分评估临床疗效，并与治疗前评分进行比较。
结果
完成研究后，与治疗前相比，这些患者的症状和体征评分有临床意义的降低。差异具有统计学意义（P < 0.01）。
结论
标准化屋尘螨变应原制剂对因屋尘螨引起的变应性鼻炎患者是一种有效的治疗方法。
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