Grimshaw Rosamund, Jain Preeti, Latthe Pallavi
Department of Obstetrics & Gynaecology, Birmingham Women's NHS Foundation Trust, Birmingham, UK.
Womens Health (Lond). 2012 Sep;8(5):567-77. doi: 10.2217/whe.12.38.
Mixed urinary incontinence accounts for 33% of all incontinence and is the involuntary loss of urine associated with the sensation of urgency; it is also associated with exertion, sneezing or coughing. Risk factors include vaginal delivery, obesity, age and possible genetic factors. Treatment includes lifestyle changes, behavioral therapies, medication and nerve modulation. Surgery with midurethral slings can cure both stress and urge components in 40-50% of cases. Future therapies may include new medications adapting potassium and calcium channels and more widespread use of sacral neuromodulation. This review focuses on the investigation and optimal management of mixed urinary incontinence.
混合性尿失禁占所有尿失禁病例的33%，是与尿急感相关的尿液不自主流失；它还与用力、打喷嚏或咳嗽有关。风险因素包括经阴道分娩、肥胖、年龄以及可能的遗传因素。治疗方法包括生活方式改变、行为疗法、药物治疗和神经调节。使用尿道中段吊带的手术可在40%至50%的病例中治愈压力性和急迫性尿失禁成分。未来的治疗方法可能包括采用钾离子和钙离子通道的新型药物以及更广泛地使用骶神经调节。本综述重点关注混合性尿失禁的研究和最佳管理。
