Luridiana S, Mura M C, Pazzola M, Paludo M, Cosso G, Dettori M L, Bua S, Vacca G M, Carcangiu V
Dipartimento di Biologia Animale, Università degli Studi di Sassari, Via Vienna 2, 07100, Sassari, Italy.
Reprod Fertil Dev. 2012;24(7):983-7. doi: 10.1071/RD11297.
A melatonin receptor 1A (MTNR1A) gene polymorphism in adult buffaloes has been reported to affect reproductive seasonality. Consequently, the aim of the present study was to assess whether this polymorphism can affect age at first conception and the interval between first and second calving in Mediterranean Italian buffaloes. The allelic frequency of the C and T alleles was 0.44 and 0.56, respectively, whereas the genotypic frequency was 26% for C/C, 40% for C/T and 34% for T/T. The average age at first mating was approximately 20 months, whereas that at calving was approximately 32 months. The largest number of calvings of primiparous buffaloes was recorded between June and October. No associations between genotype, first mating and subsequent calving date were found. The duration from first to second calving was longer in buffaloes with the C/C genotype compared with those with the T/T and C/T genotypes (P<0.01). The period of calving for buffaloes with the C/C genotype was mainly from July to September, whereas that for buffaloes with the T/T genotype was largely from March to May. The MTNR1A gene had no effect on the age of first conception in Mediterranean Italian buffaloes. Rather, the association between the T/T genotype and reproductive activity during days with a long photoperiod indicates that this polymorphism may be considered a genetic marker to identify buffaloes that are able to reproduce out of the breeding season.
据报道，成年水牛的褪黑素受体1A（MTNR1A）基因多态性会影响繁殖季节性。因此，本研究的目的是评估这种多态性是否会影响意大利地中海地区水牛的初产年龄以及头胎和二胎产犊间隔。C和T等位基因的等位基因频率分别为0.44和0.56，而基因型频率分别为：C/C型26%，C/T型40%，T/T型34%。首次配种的平均年龄约为20个月，而产犊时的平均年龄约为32个月。初产水牛的产犊数量最多记录在6月至10月之间。未发现基因型、首次配种和后续产犊日期之间存在关联。与T/T型和C/T型水牛相比，C/C型水牛从首次到第二次产犊的持续时间更长（P<0.01）。C/C型水牛的产犊期主要在7月至9月，而T/T型水牛的产犊期主要在3月至5月。MTNR1A基因对意大利地中海地区水牛的初产年龄没有影响。相反，T/T基因型与长光照期天数的繁殖活动之间的关联表明，这种多态性可被视为一种遗传标记，用于识别能够在繁殖季节外繁殖的水牛。
