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环状肉芽肿与皮肤边缘区淋巴瘤相关:一例将血液系统恶性肿瘤与肉芽肿性皮炎相联系的病例。

Granuloma annulare associated with cutaneous marginal zone lymphoma: a case linking a hematologic malignancy with granulomatous dermatitis.

作者信息

Wanat Karolyn A, Elenitsas Rosalie, Kim Ellen J, Rosenbach Misha

机构信息

Department of Dermatology, University of Pennsylvania, Philadelphia, PA 19104, USA.

出版信息

Am J Dermatopathol. 2012 Dec;34(8):844-6. doi: 10.1097/DAD.0b013e31825f2606.

Abstract

Granuloma annulare and other granulomatous disorders have been reported to be associated with internal malignancies, primarily T-cell lymphomas, whereas very few reports of granulomatous disorders in association with B-cell lymphoma exist in the literature. We report a case of marginal zone lymphoma, a cutaneous B-cell lymphoma that occurred concomitantly with refractory granuloma annulare. This case highlights the importance of considering both B- and T-cell dyscrasias in the case of refractory or extensive granulomatous lesions and the importance of histopathologic examination in the evaluation of these lesions.

摘要

据报道,环状肉芽肿和其他肉芽肿性疾病与内部恶性肿瘤有关,主要是T细胞淋巴瘤,而文献中关于肉芽肿性疾病与B细胞淋巴瘤相关的报道极少。我们报告一例边缘区淋巴瘤,一种皮肤B细胞淋巴瘤,它与难治性环状肉芽肿同时发生。该病例强调了在难治性或广泛性肉芽肿性病变情况下考虑B细胞和T细胞发育异常的重要性,以及组织病理学检查在评估这些病变中的重要性。

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