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甲状腺癌的组织学罕见性。

The histological rarity of thyroid cancer.

机构信息

Hospital Heliópolis, São Paulo, SP, Brasil.

出版信息

Braz J Otorhinolaryngol. 2012 Jul-Aug;78(4):48-51. doi: 10.1590/S1808-86942012000400010.

DOI:10.1590/S1808-86942012000400010
PMID:22936136
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9446205/
Abstract

UNLABELLED

Thyroid cancer is the most common endocrine cancer, accounting for about 1% of all cancers. Sarcomas, lymphomas and metastases to the thyroid gland are rare and only with a handful of descriptions in the literature.

OBJECTIVE

To describe rare histological types of thyroid cancer found in a reference center.

METHODS

Medical chart review from admitted patients diagnosed with thyroid cancer in the period from 1977 to 2010. Demographic, diagnostic, therapeutic and histopathological information were collected.

RESULTS

3,018 records of patients admitted with thyroid disease were reviewed. Among the cases diagnosed with rare tumors there was a predominance of: anaplastic carcinoma: 22 cases (0.7%), followed by 11 cases of medullary carcinoma (0.36%); 2 cases of sarcoma (0.07%), 2 cases of lymphoma (0.07%) and one case of metastatic carcinoid tumor (0.03%). There were more females diagnosed (57%) as well as Caucasians (84%). The most frequent clinical presentation was a palpable thyroid nodule. All patients with lymphoma, sarcoma and anaplastic carcinoma died.

CONCLUSION

Sarcomas, lymphomas and thyroid metastases are uncommon and tend to worse outcomes.

摘要

未注明

甲状腺癌是最常见的内分泌癌,约占所有癌症的 1%。肉瘤、淋巴瘤和甲状腺转移瘤很少见,文献中只有少数描述。

目的

描述在参考中心发现的罕见组织学类型的甲状腺癌。

方法

对 1977 年至 2010 年期间在我院确诊为甲状腺癌的住院患者的病历进行回顾性分析。收集人口统计学、诊断、治疗和组织病理学信息。

结果

共回顾了 3018 例患有甲状腺疾病的患者记录。在诊断为罕见肿瘤的病例中,以未分化癌为主:22 例(0.7%),其次是 11 例髓样癌(0.36%);2 例肉瘤(0.07%),2 例淋巴瘤(0.07%)和 1 例转移性类癌瘤(0.03%)。诊断为女性(57%)和白种人(84%)的患者更多。最常见的临床表现是可触及的甲状腺结节。所有患有淋巴瘤、肉瘤和未分化癌的患者均死亡。

结论

肉瘤、淋巴瘤和甲状腺转移瘤并不常见,且预后较差。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2902/9446205/dc1f3d8b4bc0/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2902/9446205/94a214291dda/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2902/9446205/9b9fe9fa97b7/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2902/9446205/dc1f3d8b4bc0/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2902/9446205/94a214291dda/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2902/9446205/9b9fe9fa97b7/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2902/9446205/dc1f3d8b4bc0/gr3.jpg

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本文引用的文献

1
[Thyroid gland primary leiomyosarcoma].[甲状腺原发性平滑肌肉瘤]
Arq Bras Endocrinol Metabol. 2010 Mar;54(3):326-30. doi: 10.1590/s0004-27302010000300012.
2
Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer.美国甲状腺协会修订的甲状腺结节和分化型甲状腺癌患者管理指南。
Thyroid. 2009 Nov;19(11):1167-214. doi: 10.1089/thy.2009.0110.
3
Poorly differentiated and anaplastic thyroid cancer.低分化及未分化甲状腺癌。
以 Superior Vena Cava 综合征为表现的原发性未分化多形性甲状腺肉瘤:一例报告
Cureus. 2021 Dec 2;13(12):e20104. doi: 10.7759/cureus.20104. eCollection 2021 Dec.
4
Spindle cell sarcoma of thyroid: a case report.甲状腺梭形细胞肉瘤:一例报告
Indian J Surg Oncol. 2014 Dec;5(4):312-4. doi: 10.1007/s13193-014-0356-x. Epub 2014 Oct 8.
5
Thyroid nodule in an eighteen-year-old man as the first presentation of acute lymphoblastic leukemia.一名18岁男性的甲状腺结节作为急性淋巴细胞白血病的首发表现。
Int J Endocrinol Metab. 2014 Jul 1;12(3):e17364. doi: 10.5812/ijem.17364. eCollection 2014 Jul.
6
Thyroid nodule as a first manifestation of Hodgkin lymphoma-report of two cases and literature review.甲状腺结节为霍奇金淋巴瘤的首发表现:两例报告并文献复习。
Diagn Pathol. 2013 Jul 15;8:116. doi: 10.1186/1746-1596-8-116.
Cancer Control. 2006 Apr;13(2):119-28. doi: 10.1177/107327480601300206.
4
Metastasis to the thyroid diagnosed by fine-needle aspiration biopsy.通过细针穿刺活检诊断为甲状腺转移。
Clin Endocrinol (Oxf). 2005 Feb;62(2):236-41. doi: 10.1111/j.1365-2265.2005.02206.x.
5
[Non-Hodgkin's lymphoma in the thyroid: case report].[甲状腺非霍奇金淋巴瘤:病例报告]
Arq Bras Endocrinol Metabol. 2004 Jun;48(3):414-8. doi: 10.1590/s0004-27302004000300014. Epub 2004 Aug 26.
6
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7
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Cancer. 1997 Feb 1;79(3):579-87. doi: 10.1002/(sici)1097-0142(19970201)79:3<579::aid-cncr22>3.0.co;2-#.
8
Metastasis to the thyroid gland. A report of 43 cases.甲状腺转移瘤。43例报告。
Cancer. 1997 Feb 1;79(3):574-8. doi: 10.1002/(sici)1097-0142(19970201)79:3<574::aid-cncr21>3.0.co;2-#.
9
Clinical aspects of primary thyroid lymphoma: diagnosis and treatment based on our experience of 119 cases.原发性甲状腺淋巴瘤的临床特点:基于119例病例的诊断与治疗经验
Thyroid. 1993 Summer;3(2):93-9. doi: 10.1089/thy.1993.3.93.
10
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Histopathology. 1985 Jan;9(1):81-97. doi: 10.1111/j.1365-2559.1985.tb02972.x.