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Seasonal and pandemic (A/H1N1 2009) MF-59-adjuvanted influenza vaccines in complete remission non-Hodgkin lymphoma patients previously treated with rituximab containing regimens.季节性流感疫苗和大流行（2009年甲型H1N1流感）MF-59佐剂流感疫苗在先前接受含利妥昔单抗方案治疗的完全缓解非霍奇金淋巴瘤患者中的应用。
Blood. 2012 Aug 30;120(9):1954-7. doi: 10.1182/blood-2012-06-438689.
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Rituximab blocks protective serologic response to influenza A (H1N1) 2009 vaccination in lymphoma patients during or within 6 months after treatment.利妥昔单抗在治疗期间或治疗后 6 个月内阻止淋巴瘤患者对甲型 H1N1 流感 2009 疫苗产生保护性血清应答。
Blood. 2011 Dec 22;118(26):6769-71. doi: 10.1182/blood-2011-08-372649. Epub 2011 Nov 4.
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Impaired response to influenza vaccine associated with persistent memory B cell depletion in non-Hodgkin's lymphoma patients treated with rituximab-containing regimens.利妥昔单抗联合方案治疗的非霍奇金淋巴瘤患者对流感疫苗反应受损与持续性记忆 B 细胞耗竭相关。
J Immunol. 2011 May 15;186(10):6044-55. doi: 10.4049/jimmunol.1004095. Epub 2011 Apr 15.
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The response to vaccination against influenza A(H1N1) 2009, seasonal influenza and Streptococcus pneumoniae in adult outpatients with ongoing treatment for cancer with and without rituximab.2009年甲型H1N1流感、季节性流感和肺炎链球菌疫苗接种对正在接受癌症治疗的成年门诊患者（使用或未使用利妥昔单抗）的反应。
Acta Oncol. 2014 Sep;53(9):1212-20. doi: 10.3109/0284186X.2014.914243. Epub 2014 May 28.
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Inactivated seasonal influenza vaccines increase serum antibodies to the neuraminidase of pandemic influenza A(H1N1) 2009 virus in an age-dependent manner.灭活季节性流感疫苗会使血清中针对 2009 年大流行的甲型流感病毒（H1N1）神经氨酸酶的抗体呈年龄依赖性增加。
J Infect Dis. 2010 Dec 1;202(11):1634-8. doi: 10.1086/657084. Epub 2010 Oct 27.
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Cross-reactive antibody responses to the 2009 pandemic H1N1 influenza virus.对2009年甲型H1N1流感大流行病毒的交叉反应性抗体应答。
N Engl J Med. 2009 Nov 12;361(20):1945-52. doi: 10.1056/NEJMoa0906453. Epub 2009 Sep 10.
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An indirect comparison meta-analysis of AS03 and MF59 adjuvants in pandemic influenza A(H1N1)pdm09 vaccines.AS03 和 MF59 佐剂在大流行性流感 A(H1N1)pdm09 疫苗中的间接比较荟萃分析。
Vaccine. 2019 Jul 18;37(31):4246-4255. doi: 10.1016/j.vaccine.2019.06.039. Epub 2019 Jun 26.
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Development and characterization of a panel of cross-reactive monoclonal antibodies generated using H1N1 influenza virus.利用H1N1流感病毒产生的一组交叉反应性单克隆抗体的研发与特性分析
Immunobiology. 2015 Aug;220(8):941-6. doi: 10.1016/j.imbio.2015.02.002. Epub 2015 Feb 14.
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Serological response to influenza A H1N1 vaccine (Pandemrix®) and seasonal influenza vaccine 2009/2010 in renal transplant recipients and in hemodialysis patients.肾移植受者和血液透析患者对甲型 H1N1 流感疫苗（Pandemrix®）和 2009/2010 季节性流感疫苗的血清学反应。
Med Microbiol Immunol. 2012 Aug;201(3):297-302. doi: 10.1007/s00430-012-0231-8. Epub 2012 Feb 17.
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Impact of pre-existing immunity on the induction of functional cross-reactive anti-hemagglutinin stalk antibodies following vaccination with an AS03 adjuvanted pandemic H1N1 vaccine.AS03 佐剂季节性流感 H1N1 疫苗接种后，预先存在的免疫对功能性交叉反应性抗血凝素茎抗体诱导的影响。
Vaccine. 2018 Apr 12;36(16):2213-2219. doi: 10.1016/j.vaccine.2018.02.022. Epub 2018 Mar 13.
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Delayed but successful development of immune memory against SARS-COV-2 after B cell-depleting monotherapy.在B细胞清除单克隆治疗后，针对SARS-CoV-2的免疫记忆出现延迟但成功发展。
Infection. 2025 May 7. doi: 10.1007/s15010-025-02544-6.
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Effectiveness, immunogenicity, and safety of COVID-19 vaccines for individuals with hematological malignancies: a systematic review.COVID-19 疫苗在血液系统恶性肿瘤患者中的有效性、免疫原性和安全性：系统评价。
Blood Cancer J. 2022 May 31;12(5):86. doi: 10.1038/s41408-022-00684-8.
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Efficacy of inactivated vaccines in patients treated with immunosuppressive drug therapy.免疫抑制药物治疗患者使用灭活疫苗的效果。
Pharmacotherapy. 2022 Apr;42(4):334-342. doi: 10.1002/phar.2671. Epub 2022 Feb 18.
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Anti-CD20 monoclonal antibodies inhibit seropositive response to Covid-19 vaccination in non-Hodgkin lymphoma patients within 6 months after treatment.抗 CD20 单克隆抗体可抑制治疗后 6 个月内非霍奇金淋巴瘤患者对 COVID-19 疫苗接种的血清阳性反应。
Exp Hematol. 2022 Mar;107:20-23. doi: 10.1016/j.exphem.2021.12.396. Epub 2021 Dec 22.
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B-Cell Immunophenotyping to Predict Vaccination Outcome in the Immunocompromised - A Systematic Review.B 细胞免疫表型分析预测免疫功能低下患者疫苗接种结局的系统评价
Front Immunol. 2021 Sep 7;12:690328. doi: 10.3389/fimmu.2021.690328. eCollection 2021.
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Influenza Vaccination Rates Among Patients With a History of Cancer: Analysis of the National Health Interview Survey.癌症病史患者的流感疫苗接种率：美国国家健康访谈调查分析
Open Forum Infect Dis. 2021 Apr 20;8(7):ofab198. doi: 10.1093/ofid/ofab198. eCollection 2021 Jul.
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Vaccine response following anti-CD20 therapy: a systematic review and meta-analysis of 905 patients.抗 CD20 治疗后的疫苗反应：905 例患者的系统评价和荟萃分析。
Blood Adv. 2021 Jun 21;5(12):2624-2643. doi: 10.1182/bloodadvances.2021004629.
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Hairy cell leukemia and COVID-19 adaptation of treatment guidelines.毛细胞白血病与 COVID-19 治疗指南的适应性调整。
Leukemia. 2021 Jul;35(7):1864-1872. doi: 10.1038/s41375-021-01257-7. Epub 2021 May 4.
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2021 update of the AGIHO guideline on evidence-based management of COVID-19 in patients with cancer regarding diagnostics, viral shedding, vaccination and therapy.2021 年更新的癌症患者 COVID-19 诊治临床实践指南：基于循证医学的管理建议，涵盖诊断、病毒排出、疫苗接种和治疗。
Eur J Cancer. 2021 Apr;147:154-160. doi: 10.1016/j.ejca.2021.01.033. Epub 2021 Feb 10.
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Influenza Vaccination Documentation Rates During the First Year After Diagnosis of Diffuse Large B Cell Lymphoma.弥漫性大 B 细胞淋巴瘤诊断后第一年的流感疫苗接种记录率。
Clin Lymphoma Myeloma Leuk. 2019 Apr;19(4):239-243. doi: 10.1016/j.clml.2018.12.018. Epub 2019 Jan 2.
本文引用的文献
1
Rituximab blocks protective serologic response to influenza A (H1N1) 2009 vaccination in lymphoma patients during or within 6 months after treatment.利妥昔单抗在治疗期间或治疗后 6 个月内阻止淋巴瘤患者对甲型 H1N1 流感 2009 疫苗产生保护性血清应答。
Blood. 2011 Dec 22;118(26):6769-71. doi: 10.1182/blood-2011-08-372649. Epub 2011 Nov 4.
2
Impaired response to influenza vaccine associated with persistent memory B cell depletion in non-Hodgkin's lymphoma patients treated with rituximab-containing regimens.利妥昔单抗联合方案治疗的非霍奇金淋巴瘤患者对流感疫苗反应受损与持续性记忆 B 细胞耗竭相关。
J Immunol. 2011 May 15;186(10):6044-55. doi: 10.4049/jimmunol.1004095. Epub 2011 Apr 15.
3
Attenuated antibody reaction for the primary antigen but not for the recall antigen of influenza vaccination in patients with non-Hodgkin B-cell lymphoma after the administration of rituximab-CHOP.在接受利妥昔单抗-CHOP治疗的非霍奇金B细胞淋巴瘤患者中，对流感疫苗的主要抗原抗体反应减弱，但对回忆抗原的抗体反应未减弱。
J Clin Exp Hematop. 2009 May;49(1):9-13. doi: 10.3960/jslrt.49.9.
4
Maintenance of the plasma cell pool is independent of memory B cells.浆细胞库的维持独立于记忆B细胞。
Proc Natl Acad Sci U S A. 2008 Mar 25;105(12):4802-7. doi: 10.1073/pnas.0800555105. Epub 2008 Mar 13.
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The human spleen is a major reservoir for long-lived vaccinia virus-specific memory B cells.人类脾脏是长寿痘苗病毒特异性记忆B细胞的主要储存库。
Blood. 2008 May 1;111(9):4653-9. doi: 10.1182/blood-2007-11-123844. Epub 2008 Mar 3.
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