McNair Medical Institute, Pediatric Diabetes and Endocrinology, Baylor College of Medicine, Houston, TX 77030, USA.
Science. 2012 Aug 31;337(6098):1051-2. doi: 10.1126/science.1227506.
The lumen of the esophagus is lined with a squamous stratified epithelium. In the model of Doupé . (based on the mouse esophageal epithelium), a single population of epithelial progenitor cells (yellow) is present above the basal lamina. The epithelium is maintained, under basal conditions, by these cells, which divide and produce both more progenitor cells or differentiate into the layers of the stratified epithelium
食管的管腔衬有鳞状分层上皮。在 Doupé 的模型中(基于小鼠食管上皮),基底膜上方存在单一的上皮祖细胞群体(黄色)。在基础条件下,上皮由这些细胞维持,这些细胞分裂并产生更多的祖细胞或分化为分层上皮的层。