Krishnamurthy Vani, Shivalingiah Sheela Devi C, Ravishankar Sunila, Manjunath Gubbanna V
Department of Pathology, JSS Hospital, MG Road, Mysore, Karnataka 570004, India.
Case Rep Pathol. 2011;2011:929654. doi: 10.1155/2011/929654. Epub 2011 Oct 24.
Carcinosarcoma is a rare tumor composed of variable proportions of carcinomatous and sarcomatous elements and comprises less than one percent of all gallbladder malignancies. In most reported cases of carcinosarcoma of gallbladder, the epithelial component is adenocarcinoma. The mesenchymal component varies from homogenous sarcoma to more heterotopic elements like malignant bone, cartilage, and other mesenchymal tissues. We report a rare case of carcinosarcoma of the gallbladder in an 83-year-old male, with the carcinomatous component represented by undifferentiated carcinoma (spindle and giant cell type with osteoclastic giant cells) and the mesenchymal component seen as foci of chondrosarcoma.
癌肉瘤是一种罕见肿瘤，由不同比例的癌性和肉瘤性成分组成，占所有胆囊恶性肿瘤的比例不到1%。在大多数已报道的胆囊癌肉瘤病例中，上皮成分是腺癌。间充质成分从均质肉瘤到更异源性成分，如恶性骨、软骨和其他间充质组织不等。我们报告一例83岁男性胆囊癌肉瘤的罕见病例，癌性成分表现为未分化癌（伴有破骨巨细胞的梭形和巨细胞型），间充质成分表现为软骨肉瘤灶。
