Department of Surgery, Chonnam National University Medical School, 160, Ilsim-ri, Hwasun-eup, Hwasun-gun, Jellanam-do, Gwangju, 519-809, Korea.
Surg Today. 2012 Jul;42(7):670-5. doi: 10.1007/s00595-012-0160-6. Epub 2012 Mar 6.
Adenocarcinoma is the predominant histological type of carcinoma of the gallbladder, accounting for more than 80% of all gallbladder carcinomas. In contrast, carcinosarcoma of the gallbladder is an extremely atypical subset of gallbladder malignancies. It is characterized by the presence of both epithelial and mesenchymal components. Currently, fewer than 100 cases have been reported in the English literature. Therefore, knowledge and experience regarding this disease are limited. Recently, we experienced two cases of gallbladder carcinosarcoma, which were diagnosed as gallbladder carcinoma based on the preoperative clinical and radiological examinations. Cholecystectomies were performed in both cases, and the malignant tumor cells included carcinomatous and sarcomatous components histologically. The final pathological diagnoses were carcinosarcoma of the gallbladder. We herein report these two cases of gallbladder carcinosarcoma and review the previous pertinent literature.
胆囊腺癌是胆囊癌的主要组织学类型，占所有胆囊癌的 80%以上。相比之下，胆囊肉瘤是一种极其罕见的胆囊恶性肿瘤亚型。其特征是同时存在上皮和间叶成分。目前，英文文献中报道的病例不足 100 例。因此，对于这种疾病的认识和经验有限。最近，我们遇到了两例胆囊肉瘤，根据术前临床和影像学检查，被诊断为胆囊癌。两例均行胆囊切除术，组织学上恶性肿瘤细胞包括癌性和肉瘤性成分。最终的病理诊断为胆囊肉瘤。我们在此报告两例胆囊肉瘤，并复习相关文献。
