Mansour Subhi, Derkach Elena, Abergil Valerya, Khuri Safi
General Surgery Department, Rambam Health Care Campus, Haifa, Israel.
Operating Room, Rambam Health Care Campus, Haifa, Israel.
World J Oncol. 2022 Jun;13(3):103-106. doi: 10.14740/wjon1495. Epub 2022 Jun 22.
Malignant tumors of the gallbladder are rare, with adenocarcinoma being the most common histological subtype. Carcinosarcoma of the gallbladder, first described in 1907 by Landsteiner, is an extremely rare tumor which comprises less than 1% of the uncommon gallbladder cancers. This unique type of tumor can develop at any major organ, with the uterus being the most common one. Being a tumor that contains epithelial and mesenchymal components, histopathological diagnosis of such rare tumor is a challenging issue. Up to date, there are less than 100 cases of gallbladder carcinoasarocoma reported in the English literature. Therefore, experience and knowledge regarding this rare disease are very limited. Due to the fact that gallbladder carcinosarcoma is a rare and highly forgotten tumor, this article aims to review the English literature to increase awareness of the treating physician to improve diagnosis, management, as well as overall survival.
胆囊恶性肿瘤较为罕见，腺癌是最常见的组织学亚型。胆囊癌肉瘤于1907年由兰德施泰纳首次描述，是一种极其罕见的肿瘤，在不常见的胆囊癌中所占比例不到1%。这种独特类型的肿瘤可发生于任何主要器官，其中子宫最为常见。作为一种包含上皮和间充质成分的肿瘤，对这种罕见肿瘤进行组织病理学诊断是一个具有挑战性的问题。截至目前，英文文献中报道的胆囊癌肉瘤病例不到100例。因此，关于这种罕见疾病的经验和知识非常有限。由于胆囊癌肉瘤是一种罕见且极易被遗忘的肿瘤，本文旨在回顾英文文献，以提高治疗医生的认识，从而改善诊断、治疗及总体生存率。
