Université Francois Rabelais de Tours, France.
J Cosmet Dermatol. 2012 Sep;11(3):201-6. doi: 10.1111/j.1473-2165.2012.00627.x.
Certain authors have reported the efficacy of fractional resurfacing laser treatment in patients with photodamaged skin resulting in skin tightening of treated area.
To assess skin tightening after CO(2) fractional resurfacing laser treatment by measuring variations in mechanical properties in treated areas. Dermal elasticity was measured using suction applied with an in vivo skin elasticity meter (Cutometer(®)).
A prospective observational study was undertaken from January 2007 to August 2009. Laser treatment was performed with the SmartXide Dot(®) (Deka(®), Firenze, Italy) CO(2) fractional resurfacing device. Patients were offered quantified analysis using the Cutometer(®) before and after treatment.
Seventeen patients (61 areas treated) were included in the study. Median delay between before and after cutometric evaluations was 80 days. We found significant improvement in elastic (R2 +5.9%), viscoelastic (R8 -9.4%), fatigue (R3 and R9 -16.2% and -19.7%, respectively), and thickness (R0 -14.9%) parameters. These results are consistent with significant tightening and also elastic tissue improvement.
It was possible to quantify skin tightening because of CO(2) fractional laser treatment using a noninvasive technique.
一些作者曾报道过，在治疗光老化皮肤时，应用分波长 CO2 激光能有效改善皮肤质地，使治疗区域皮肤收紧。
通过测量治疗区域机械特性的变化，评估 CO2 分波长激光治疗后的皮肤紧致度。采用体内皮肤弹性测量计（Cutometer）对真皮弹性进行测量。
前瞻性观察研究，于 2007 年 1 月至 2009 年 8 月进行。采用 SmartXide Dot（Deka，佛罗伦萨，意大利）CO2 分波长激光治疗设备进行激光治疗。在治疗前后，患者可接受 Cutometer 定量分析。
本研究共纳入 17 例患者（共 61 个治疗区域）。两次皮肤弹性测量的中位间隔为 80 天。我们发现弹性（R2 +5.9%）、黏性（R8 -9.4%）、疲劳（R3 和 R9 -16.2%和-19.7%）和厚度（R0 -14.9%）参数均显著改善。这些结果与皮肤收紧和弹性组织改善相一致。
采用非侵入性技术，我们可以对 CO2 分波长激光治疗后皮肤的收紧程度进行定量评估。
