Shoji Kensuke, Komuro Hisako, Kobayashi Yoshinori, Shike Tatsuhiko, Funaki Takanori, Katsuta Tomohiro, Miyata Ippei, Saitoh Akihiko
Division of Infectious Disease, Department of Medical Subspecialties, National Center for Child Health and Development, Tokyo, JapanDivision of General Pediatrics, Department of Interdisciplinary Medicine, National Center for Child Health and Development, Tokyo, Japan.
Pediatr Dermatol. 2014 Mar-Apr;31(2):258-9. doi: 10.1111/j.1525-1470.2012.01819.x. Epub 2012 Sep 3.
Human parechovirus type 3 (HPeV3) is known to cause sepsis-like syndrome and meningoencephalitis in neonates and young infants. We herein report a neonatal case of sepsis-like syndrome due to HPeV3 infection, diagnosed using polymerase chain reaction (PCR), with a distinctive erythematous rash present mainly on the soles and palms that helped in the diagnosis of the disease. Combining the unique characteristics of rash and confirmation by PCR at the early stage of the disease led to the diagnosis of HPeV3, distinguishing it from sepsis and other critical disease conditions, and allowing for appropriate, rapid management.
已知3型人细小病毒（HPeV3）可在新生儿和幼儿中引起败血症样综合征和脑膜脑炎。我们在此报告一例因HPeV3感染导致败血症样综合征的新生儿病例，该病例通过聚合酶链反应（PCR）诊断，其特征为主要出现在足底和手掌的独特红斑疹，这有助于疾病的诊断。结合皮疹的独特特征以及在疾病早期通过PCR确诊，从而诊断出HPeV3，将其与败血症和其他严重疾病情况区分开来，并实现了适当、快速的治疗。
