Erdurman F Cuneyt, Pellumbi Alfrida, Durukan A Hakan
Department of Ophthalmology, Gulhane Military Medical Academy and School of Medicine, Ankara, Turkey.
Ophthalmic Surg Lasers Imaging. 2012 Aug 30;43 Online:e87-9. doi: 10.3928/15428877-20120823-05.
A 49-year-old woman with a diagnosis of diabetic cystoid macular edema in both eyes presented with the appearance of a macular hole in the left eye 1 month after intravitreal bevacizumab injection. Optical coherence tomography demonstrated a lamellar macular hole in the left eye. Although vitreomacular traction and epiretinal membrane are the possible underlying causes for the development of lamellar macular hole formation in eyes with cystoid macular edema, in this case previous optical coherence tomography scans revealed the complete separation of the posterior hyaloid membrane and the absence of an epiretinal membrane. The exact mechanism involved in the progression of cystoid macular edema to lamellar macular hole and the contribution of the intravitreal bevacizumab injections to this transformation remain unclear.
一名49岁双眼诊断为糖尿病性黄斑囊样水肿的女性，在玻璃体内注射贝伐单抗1个月后左眼出现黄斑裂孔。光学相干断层扫描显示左眼为板层黄斑裂孔。尽管玻璃体黄斑牵引和视网膜前膜可能是黄斑囊样水肿眼发生板层黄斑裂孔的潜在原因，但在本例中，先前的光学相干断层扫描显示后玻璃体膜完全分离且无视网膜前膜。黄斑囊样水肿进展为板层黄斑裂孔的确切机制以及玻璃体内注射贝伐单抗对这种转变的作用仍不清楚。
