Prasad N, Wright D A, Ford J J, Thornby J I
Department of Radiology, Baylor College of Medicine, Houston, TX 77030.
Radiology. 1990 Jan;174(1):251-3. doi: 10.1148/radiology.174.1.2294557.
Fertilized eggs of Rana pipiens (leopard frogs) were exposed to 0.15- or 4.5-T magnetic resonance (MR) imaging and were compared with unexposed fertilized eggs with respect to the percentage of embryos cleaving and percentage of tail buds forming normally. Similarly exposed or unexposed sperm were used to fertilize unexposed eggs, and the same parameters were observed. There was no evidence that MR imaging exposure at 0.15 or 4.5 T had any effect on cleaving embryos or tail bud formation. Since embryogenesis in amphibians is very sensitive to foreign insult, the authors conclude that exposure to a magnetic field of up to 4.5 T has no adverse effect on early development.
将豹蛙的受精卵暴露于0.15特斯拉或4.5特斯拉的磁共振（MR）成像环境中，并就胚胎分裂百分比和正常形成尾芽的百分比，将其与未暴露的受精卵进行比较。使用同样暴露或未暴露的精子使未暴露的卵子受精，并观察相同的参数。没有证据表明0.15特斯拉或4.5特斯拉的MR成像暴露对分裂期胚胎或尾芽形成有任何影响。由于两栖动物的胚胎发生对外来损伤非常敏感，作者得出结论，暴露于高达4.5特斯拉的磁场对早期发育没有不利影响。
