School of Chemistry, University of Bristol, Cantock's Close, Bristol, BS8 1TS, UK.
Adv Mater. 2012 Dec 4;24(46):6244-7. doi: 10.1002/adma.201202685. Epub 2012 Sep 4.
DNA chains and their movement in solvent may now be controlled simply by surfactant binding and the switching "on" and "off" of a magnetic field adding a new paradigm to the study and control, condensation and manipulation of DNA (and other biomolecules). Such control is essential for biotechnological applications such as transfection and the regulation of gene suppression, as well as in materials science concerning soft molecular self-assemblies.
DNA 链及其在溶剂中的运动现在可以通过表面活性剂的结合以及磁场的“开”和“关”来简单地控制,这为 DNA(和其他生物分子)的研究、控制、浓缩和操作增添了一个新的范例。这种控制对于转染和基因抑制的调控等生物技术应用以及涉及软分子自组装的材料科学都是至关重要的。