Guilleminault C, Ariagno R, Korobkin R, Nagel L, Baldwin R, Coons S, Owen M
Pediatrics. 1979 Dec;64(6):882-91.
Twenty-nine full-term near miss for sudden infant death syndrome (SIDS) and 30 normal control infants underwent 24-hour polygraphic monitoring. Several types of respiratory events during sleep (eg, central, mixed, and obstructive apnea, periodic breathing) were defined and tabulated. Analysis of these respiratory variables and comparison of groups of near miss and control infants indicated that between 3 weeks and 4 1/2 months of age only one variable was consistently different at a statistically significant level: the number of mixed and obstructive apnea greater than 3 seconds during total sleep time. This study also showed an increase in mixed and obstructive respiratory events during sleep at 6 weeks of age in control as well as in near miss infants.
29名足月的婴儿猝死综合征(SIDS)濒死儿和30名正常对照婴儿接受了24小时多导睡眠监测。定义并列表记录了睡眠期间的几种呼吸事件类型(如中枢性、混合性和阻塞性呼吸暂停、周期性呼吸)。对这些呼吸变量进行分析,并对濒死儿组和对照婴儿组进行比较,结果表明,在3周龄至4个半月龄之间,只有一个变量在统计学显著水平上始终存在差异:总睡眠时间内持续超过3秒的混合性和阻塞性呼吸暂停次数。这项研究还表明,在6周龄时,对照婴儿和濒死儿在睡眠期间的混合性和阻塞性呼吸事件均有所增加。