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维生素 D 与黑色素瘤发病和死亡风险。

Vitamin D and melanoma incidence and mortality.

机构信息

Division of Epidemiology, Biostatistics and Preventive Medicine, Department of Internal Medicine, University of New Mexico Cancer Center, Albuquerque, NM, USA.

出版信息

Pigment Cell Melanoma Res. 2013 Jan;26(1):9-15. doi: 10.1111/pcmr.12015. Epub 2012 Oct 24.

DOI:10.1111/pcmr.12015
PMID:22947439
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3734794/
Abstract

The role of vitamin D (25-OH-D, or 25-hydroxyvitamin D) and its potential confounders in relationship to melanoma risk and mortality is discussed. The paradox that ultraviolet radiation (UVR) exposure is the major environmental risk factor for melanoma etiology as well as a major source of vitamin D might be explained by viewing vitamin D levels as the result of a healthy lifestyle rather than a cause of health.

摘要

本文讨论了维生素 D(25-OH-D,或 25-羟基维生素 D)及其潜在混杂因素与黑色素瘤风险和死亡率的关系。紫外线辐射(UVR)暴露既是黑色素瘤病因的主要环境风险因素,也是维生素 D 的主要来源,这种矛盾可以通过将维生素 D 水平视为健康生活方式的结果,而不是健康的原因来解释。

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Vitamin D and melanoma incidence and mortality.维生素 D 与黑色素瘤发病和死亡风险。
Pigment Cell Melanoma Res. 2013 Jan;26(1):9-15. doi: 10.1111/pcmr.12015. Epub 2012 Oct 24.
2
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To identify the association between dietary vitamin D intake and serum levels and risk or prognostic factors for melanoma-systematic review and meta-analysis.目的:明确饮食维生素 D 摄入与血清水平及黑素瘤风险或预后因素之间的关系——系统评价和荟萃分析。
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Development of novel parameter for monitoring of malignant melanoma progression.用于监测恶性黑色素瘤进展的新参数的开发。
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本文引用的文献

1
Serum 25-hydroxyvitamin D serum levels in a large German cohort of patients with melanoma.血清 25-羟维生素 D 水平在一个大型德国黑素瘤患者队列中。
Br J Dermatol. 2013 Mar;168(3):625-8. doi: 10.1111/j.1365-2133.2012.11212.x. Epub 2012 Oct 5.
2
Determination of vitamin D in relation to body mass index and race in a defined population of black and white women.在一个特定的黑人和白人女性人群中,测定维生素 D 与体重指数和种族的关系。
Int J Gynaecol Obstet. 2012 Oct;119(1):21-5. doi: 10.1016/j.ijgo.2012.05.024. Epub 2012 Jul 18.
3
High UV-A exposure from sunbeds.
Pigment Cell Melanoma Res. 2012 Sep;25(5):639-40. doi: 10.1111/j.1755-148X.2012.01035.x. Epub 2012 Aug 6.
4
Germline melanoma susceptibility and prognostic genes: a review of the literature.胚系黑色素瘤易感性和预后相关基因:文献复习。
J Am Acad Dermatol. 2012 Nov;67(5):1055-67. doi: 10.1016/j.jaad.2012.02.042. Epub 2012 May 13.
5
No association of vitamin D metabolism-related polymorphisms and melanoma risk as well as melanoma prognosis: a case-control study.维生素 D 代谢相关多态性与黑色素瘤风险及预后的相关性研究:病例对照研究。
Arch Dermatol Res. 2012 Jul;304(5):353-61. doi: 10.1007/s00403-012-1243-3. Epub 2012 May 11.
6
Pre-diagnostic circulating vitamin D and risk of melanoma in men.男性诊断前循环维生素 D 与黑色素瘤风险。
PLoS One. 2012;7(4):e35112. doi: 10.1371/journal.pone.0035112. Epub 2012 Apr 25.
7
Vitamin D status as an international issue: national surveys and the problem of standardization.维生素D状况作为一个国际问题:全国性调查与标准化问题
Scand J Clin Lab Invest Suppl. 2012;243:32-40. doi: 10.3109/00365513.2012.681935.
8
Vitamin D receptor mediates DNA repair and is UV inducible in intact epidermis but not in cultured keratinocytes.维生素D受体介导DNA修复,在完整表皮中可被紫外线诱导,但在培养的角质形成细胞中则不然。
J Invest Dermatol. 2012 Aug;132(8):2097-100. doi: 10.1038/jid.2012.107. Epub 2012 Apr 12.
9
Predictors of serum vitamin D levels in African American and European American men in Chicago.芝加哥非裔美国男性和欧裔美国男性血清维生素 D 水平的预测因素。
Am J Mens Health. 2012 Sep;6(5):420-6. doi: 10.1177/1557988312437240. Epub 2012 Mar 7.
10
Cross-sectional and prospective cohort study of serum 25-hydroxyvitamin D level and obesity in adults: the HUNT study.横断面和前瞻性队列研究血清 25-羟维生素 D 水平与成年人肥胖的关系:HUNT 研究。
Am J Epidemiol. 2012 May 15;175(10):1029-36. doi: 10.1093/aje/kwr456. Epub 2012 Feb 6.