• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

危重病临床研究:告别过山车。

Critical care clinical trials: getting off the roller coaster.

机构信息

Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, Medical University of South Carolina, Charleston, SC.

出版信息

Chest. 2012 Sep;142(3):563-567. doi: 10.1378/chest.12-0519.

DOI:10.1378/chest.12-0519
PMID:22948575
Abstract

Optimizing care in the ICU is an important goal. The heightened severity of illness in patients who are critically ill combined with the tremendous costs of critical care make the ICU an ideal target for improvement in outcomes and efficiency. Incorporation of evidence-based medicine into everyday practice is one method to optimize care; however, intensivists have struggled to define optimal practices because clinical trials in the ICU have yielded conflicting results. This article reviews examples where such conflicts have occurred and explores possible causes of these discrepant data as well as strategies to better use critical care clinical trials in the future.

摘要

优化 ICU 护理是一个重要目标。危重症患者的病情严重程度加剧,加上重症监护的巨大费用,使得 ICU 成为改善预后和提高效率的理想目标。将循证医学纳入日常实践是优化护理的一种方法;然而,重症医学专家一直在努力确定最佳实践,因为 ICU 中的临床试验得出了相互矛盾的结果。本文回顾了出现这种冲突的例子,并探讨了这些数据差异的可能原因以及未来更好地利用重症监护临床试验的策略。

相似文献

1
Critical care clinical trials: getting off the roller coaster.危重病临床研究:告别过山车。
Chest. 2012 Sep;142(3):563-567. doi: 10.1378/chest.12-0519.
2
Finding out what we do in the ICU.了解我们在重症监护室里的工作内容。
Crit Care Med. 2006 Jan;34(1):227-8. doi: 10.1097/01.ccm.0000196215.13080.54.
3
Glucose control in the intensive care unit: a roller coaster ride or a swinging pendulum?重症监护病房中的血糖控制:是过山车之旅还是摆动的钟摆?
Ann Intern Med. 2009 Jun 2;150(11):809-11. doi: 10.7326/0003-4819-150-11-200906020-00009.
4
Effect of evidence-based feeding guidelines on mortality of critically ill adults: a cluster randomized controlled trial.循证喂养指南对危重症成年患者死亡率的影响:一项整群随机对照试验
JAMA. 2008 Dec 17;300(23):2731-41. doi: 10.1001/jama.2008.826.
5
China Spinal Cord Injury Network: changes from within.中国脊髓损伤网络:内部变革
Lancet Neurol. 2009 Jul;8(7):606-7. doi: 10.1016/S1474-4422(09)70162-0.
6
Canadian clinical practice guidelines for nutrition support in mechanically ventilated, critically ill adult patients.加拿大机械通气的危重症成年患者营养支持临床实践指南。
JPEN J Parenter Enteral Nutr. 2003 Sep-Oct;27(5):355-73. doi: 10.1177/0148607103027005355.
7
Critical care research in mainland China: more needed on the international stage.中国大陆的重症监护研究:在国际舞台上更需努力。
Intensive Care Med. 2013 Apr;39(4):768-70. doi: 10.1007/s00134-013-2853-8. Epub 2013 Feb 22.
8
Recent evidence on early mobilization in critical-Ill patients.危重症患者早期活动的最新证据。
Curr Opin Anaesthesiol. 2018 Apr;31(2):144-150. doi: 10.1097/ACO.0000000000000568.
9
Critical care medicine in the United States: addressing the intensivist shortage and image of the specialty.美国重症监护医学:解决重症医学专家短缺和专业形象问题。
Crit Care Med. 2013 Dec;41(12):2754-61. doi: 10.1097/CCM.0b013e318298a6fb.
10
The myth of the workforce crisis. Why the United States does not need more intensivist physicians.劳动力危机的神话。为何美国不需要更多的重症医师。
Am J Respir Crit Care Med. 2015 Jan 15;191(2):128-34. doi: 10.1164/rccm.201408-1477CP.

引用本文的文献

1
Effect sizes in ongoing randomized controlled critical care trials.正在进行的随机对照重症监护试验中的效应大小。
Crit Care. 2017 Jun 5;21(1):132. doi: 10.1186/s13054-017-1726-x.
2
Prone position for acute respiratory failure in adults.成人急性呼吸衰竭的俯卧位
Cochrane Database Syst Rev. 2015 Nov 13;2015(11):CD008095. doi: 10.1002/14651858.CD008095.pub2.
3
When the value of gold is zero.
BMC Res Notes. 2014 Jun 27;7:404. doi: 10.1186/1756-0500-7-404.