玻璃体内注射羟苯磺酸钙治疗年龄相关性黄斑变性伴脉络膜新生血管：两例报告
Intravitreal dobesilate in the treatment of choroidal neovascularisation associated with age-related macular degeneration: report of two cases.
作者信息
Cuevas Pedro, Outeiriño Luis, Azanza Carlos, Giménez-Gallego Guillermo
机构信息
Departamento de Investigación, IRYCIS, Hospital Universitario Ramón y Cajal, Madrid, Spain.
出版信息
BMJ Case Rep. 2012 Sep 3;2012:bcr2012006619. doi: 10.1136/bcr-2012-006619.
Abstract
This case report presents the effectiveness of intravitreal administration of dobesilate, a synthetic fibroblast growth factor inhibitor, in two patients showing neovascular age-related macular degeneration of the classic, and of the occult choroidal neovascularisation types, respectively. Our study demonstrates that the treatment induces the regression of both forms of this pathology, as assessed by spectral optical coherence tomography. Improvement of the lesions was accompanied of visual acuity improvement.
摘要
本病例报告展示了玻璃体内注射羟苯磺酸钙（一种合成的成纤维细胞生长因子抑制剂）对两名分别患有典型新生血管性年龄相关性黄斑变性和隐匿性脉络膜新生血管形成的患者的疗效。我们的研究表明，通过光谱光学相干断层扫描评估，该治疗可使这两种病理类型均出现消退。病变的改善伴随着视力的提高。
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