中耳炎患者中耳积液和血清中的溶菌酶水平

Lysozyme levels in middle ear effusion and serum in otitis media.

作者信息

Harada T, Juhn S K, Adams G L

机构信息

Department of Otolaryngology, University of Minnesota Medical School, Minneapolis.

出版信息

Arch Otolaryngol Head Neck Surg. 1990 Jan;116(1):54-6. doi: 10.1001/archotol.1990.01870010058017.

DOI:10.1001/archotol.1990.01870010058017

PMID:2294941

Abstract

Lysozyme concentrations in middle ear effusion and serum were determined in patients with otitis media with effusion. Lysozyme concentrations in middle ear effusion were significantly higher than in serum. Children with mucoid otitis media showed significantly higher levels of lysozyme in middle ear effusion than children with serous otitis media and adults with otitis media with effusion. Higher levels of lysozyme were observed in the group of children younger than 5 years old compared with the age group of 6- to 10-year-olds. Lysozyme concentrations of middle ear effusion in adults were significantly lower than those of mucoid otitis media in children. These results indicate that lysozyme plays an important role in the disease process of otitis media.

摘要

对分泌性中耳炎患者测定了中耳积液和血清中的溶菌酶浓度。中耳积液中的溶菌酶浓度显著高于血清中的溶菌酶浓度。与浆液性中耳炎患儿及分泌性中耳炎成人患者相比，黏液性中耳炎患儿的中耳积液中溶菌酶水平显著更高。与6至10岁年龄组相比，5岁以下儿童组的溶菌酶水平更高。成人分泌性中耳炎的中耳积液溶菌酶浓度显著低于儿童黏液性中耳炎的溶菌酶浓度。这些结果表明，溶菌酶在中耳炎的疾病过程中起重要作用。