Department of Medical Physics, Faculty of Life Sciences, Kumamoto University, Kuhonji, Japan.
Acad Radiol. 2012 Nov;19(11):1324-31. doi: 10.1016/j.acra.2012.06.013. Epub 2012 Aug 28.
To evaluate stent lumen visualization by combining high-resolution cardiac kernel and the iterative reconstruction (iDose) on an anthropomorphic moving heart phantom and in patients at coronary computed tomography (CT) angiography.
We used the moving heart phantom and a 64 detector-row CT, retrospectively gated helical scanning, and image reconstruction. The heart rate was set at nonpulsating condition of 0 beats/min, 50 beats/min, and 80 beats/min. The 120-kV images were reconstructed in synchronization with electrocardiogram data using filtered back projection (FBP) or iDose algorithm and standard kernel/filter (CB) or high-resolution kernel/filter (CD). We measured image noise, the kurtosis, and stent lumen diameter in the phantom study. We also assessed the visual inspections by two radiologists.
With cardiac motion at 50 and 80 beats/min, the difference of kurtosis improved with CD relative to CB (P < .05). iDose algorithm with level 7 provided lowest noise, with no statistically significance in difference of the kurtosis relative to level 4 (P > .05). Without cardiac motion at 0 beats/min, the stent lumen diameter measurements with CD kernel were better relative to CB kernel (P < .05). In addition, no significant difference was found in stent lumen diameter between iDose level 4 and level 7 (P > .05).
The use of iDose and a sharp kernel allowed improved stent visualization at a lower radiation dose.
在人体心脏运动模体和冠状动脉 CT 血管造影患者中,通过结合高分辨率心脏内核和迭代重建(iDose)技术,评估支架管腔的可视性。
我们使用心脏运动模体和 64 排探测器 CT,回顾性心电门控螺旋扫描和图像重建。心率设置为非搏动条件下的 0 次/分、50 次/分和 80 次/分。120kV 图像与心电图数据同步使用滤波反投影(FBP)或 iDose 算法和标准内核/滤波器(CB)或高分辨率内核/滤波器(CD)重建。我们在模体研究中测量图像噪声、峰度和支架管腔直径。我们还由两名放射科医生进行了视觉检查评估。
在心率为 50 次/分和 80 次/分时,CD 相对于 CB 的峰度差异改善(P<.05)。iDose 算法的 7 级提供了最低的噪声,与 4 级(P>.05)相比,峰度差异无统计学意义。在心率为 0 次/分时无心脏运动,CD 内核的支架管腔直径测量值优于 CB 内核(P<.05)。此外,iDose 4 级和 7 级之间的支架管腔直径无显著差异(P>.05)。
使用 iDose 和锐利内核可以在较低的辐射剂量下改善支架的可视性。