nBu4NI 催化的以叔丁基过氧化氢为氧化剂，水为介质，由芳基甲基酮和二烷基甲酰胺直接合成 α-酮酰胺。
nBu4NI-catalyzed direct synthesis of α-ketoamides from aryl methyl ketones with dialkylformamides in water using TBHP as oxidant.
机构信息
School of Chemistry and Chemical Engineering, Henan University of Technology, Lianhua Street, Zhengzhou, 450001, PR China.
出版信息
Chem Commun (Camb). 2012 Oct 18;48(81):10117-9. doi: 10.1039/c2cc35279f.
PMID:22951489
Abstract
A novel and easy practical direct synthesis of α-ketoamides has been developed without metals in water. This procedure was catalyzed by nBu(4)NI using TBHP as oxidant from simple substrates, aryl methyl ketones and dialkylformamides.
摘要
一种新颖且实用的α-酮酰胺的直接合成方法已经开发出来，该方法无需金属，在水中进行。该方法以 TBHP 作为氧化剂，nBu(4)NI 作为催化剂，由简单的底物（芳基甲基酮和二烷基甲酰胺）直接合成得到α-酮酰胺。
Zotero 插件