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在埃塞俄比亚南部,与玉米-大豆混合物相比,使用即食补充食品治疗中度急性营养不良可使儿童总体康复率更高:一项运营研究试验。

Treatment of moderate acute malnutrition with ready-to-use supplementary food results in higher overall recovery rates compared with a corn-soya blend in children in southern Ethiopia: an operations research trial.

机构信息

Department of Nutritional Sciences and the Dalla Lana School of Public Health, University of Toronto, Toronto, Canada.

出版信息

Am J Clin Nutr. 2012 Oct;96(4):911-6. doi: 10.3945/ajcn.111.029744. Epub 2012 Sep 5.

Abstract

BACKGROUND

Moderate and severe acute malnutrition affects 13% of children <5 y of age worldwide. Severe acute malnutrition affects fewer children but is associated with higher rates of mortality and morbidity. Supplementary feeding programs aim to treat moderate acute malnutrition and prevent the deterioration to severe acute malnutrition.

OBJECTIVE

The aim was to compare recovery rates of children with moderate acute malnutrition in supplementary feeding programs by using the newly recommended ration of ready-to-use supplementary food (RUSF) and the more conventional ration of corn-soya blend (CSB) in Ethiopia.

DESIGN

A total of 1125 children aged 6-60 mo with moderate acute malnutrition received 16 wk of CSB or RUSF. Children were randomly assigned to receive one or the other food. The daily rations were purposely based on the conventional treatment rations distributed at the time of the study in Ethiopia: 300 g CSB and 32 g vegetable oil in the control group (1413 kcal) and 92 g RUSF in the intervention group (500 kcal). The higher ration size of CSB was provided because of expected food sharing.

RESULTS

The HR for children in the CSB group was 0.85 (95% CI: 0.73, 0.99), which indicated that they had 15% lower recovery (P = 0.039). Recovery rates of children at the end of the 16-wk treatment period trended higher in the RUSF group (73%) than in the CSB group (67%) (P = 0.056).

CONCLUSION

In comparison with CSB, the treatment of moderate acute malnutrition with RUSF resulted in higher recovery rates in children, despite the large ration size and higher energy content of the conventional CSB ration.

摘要

背景

全球有 13%的 5 岁以下儿童患有中重度急性营养不良。重度急性营养不良影响的儿童较少,但与更高的死亡率和发病率相关。补充喂养计划旨在治疗中度急性营养不良,并防止病情恶化至重度急性营养不良。

目的

本研究旨在比较在埃塞俄比亚,使用新推荐的即食补充食品(RUSF)和更传统的玉米-大豆混合物(CSB)的补充喂养计划中,中度急性营养不良儿童的恢复率。

设计

共有 1125 名 6-60 月龄的中度急性营养不良儿童接受了 16 周的 CSB 或 RUSF。儿童被随机分配接受一种或另一种食物。每日配给量是根据当时在埃塞俄比亚分发的传统治疗配给量确定的:对照组(1413 千卡)提供 300 克 CSB 和 32 克植物油,干预组(500 千卡)提供 92 克 RUSF。CSB 的较高配给量是因为预计会有食物共享。

结果

CSB 组儿童的 HR 为 0.85(95%CI:0.73,0.99),这表明他们的恢复率低 15%(P = 0.039)。在 16 周治疗期末,RUSF 组儿童的恢复率(73%)高于 CSB 组(67%)(P = 0.056)。

结论

与 CSB 相比,RUSF 治疗中度急性营养不良导致儿童的恢复率更高,尽管 CSB 的配给量较大且能量含量较高。

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