Trefolane A，一种来自担子菌银耳属发酵的具有全新骨架的倍半萜。

Trefolane A, a sesquiterpenoid with a new skeleton from cultures of the basidiomycete Tremella foliacea.

机构信息

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, PR China.

出版信息

Org Lett. 2012 Sep 21;14(18):4976-8. doi: 10.1021/ol302184r. Epub 2012 Sep 6.

DOI:10.1021/ol302184r

PMID:22953776

Abstract

Trefolane A (1), an unprecedented skeleton with a 5/6/4 tricyclic ring system, was isolated from cultures of the basidiomycete Tremella foliacea. The structure was elucidated by means of spectroscopic methods and further confirmed by single crystal X-ray diffraction analysis. A possible biogenesis for trefolane A (1) was also proposed.

摘要

从担子菌银耳属真菌发酵液中分离得到一个具有 5/6/4 三环骨架的新颖倍半萜 trefolane A（1）。通过波谱方法解析其结构，并结合单晶 X 射线衍射分析进一步确证。并对其生物合成途径进行了推测。