Szatmari P, Tuff L, Finlayson M A, Bartolucci G
Department of Psychiatry, McMaster University, Hamilton, Ontario.
J Am Acad Child Adolesc Psychiatry. 1990 Jan;29(1):130-6. doi: 10.1097/00004583-199001000-00021.
The objectives of this study were to see: (1) whether children with Asperger's Syndrome (AS) have similar neurocognitive deficits compared to nonretarded, or high-functioning autistic (HFA) children; and (2) whether the essential cognitive deficit among these children is in language or abstract problem solving. Subjects with AS, HFA, and a control group of socially impaired child psychiatric outpatient controls (OPC) were compared on a battery of neuropsychological tests. The results indicated that the AS and HFA groups differed little but that large differences from the OPC were observed on all tests. When the AS and HFA with FSIQ above 85 were compared to the OPC, outstanding deficits on motor coordination, language comprehension, and facial recognition were observed. Finally, some evidence is presented to suggest that the pattern of deficits of AS and HFA subjects varied by developmental level. The implications of these results for a neurological theory of autism are discussed.
(1)与非智障或高功能自闭症(HFA)儿童相比,阿斯伯格综合征(AS)儿童是否存在类似的神经认知缺陷;以及(2)这些儿童的基本认知缺陷是在语言方面还是抽象问题解决方面。对患有AS、HFA的受试者以及一组社会功能受损的儿童精神科门诊对照(OPC)进行了一系列神经心理学测试比较。结果表明,AS组和HFA组差异不大,但在所有测试中均观察到与OPC组有很大差异。当将智商(FSIQ)高于85的AS组和HFA组与OPC组进行比较时,发现运动协调、语言理解和面部识别方面存在明显缺陷。最后,有证据表明AS组和HFA组受试者的缺陷模式因发育水平而异。讨论了这些结果对自闭症神经学理论的意义。