Division of General Medicine and Primary Care, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
J Gen Intern Med. 2013 Feb;28(2):231-8. doi: 10.1007/s11606-012-2188-0. Epub 2012 Sep 7.
Obesity is a stigmatizing condition associated with adverse psychosocial consequences. The relative importance of weight stigma in reducing health utility or the value a person places on their current health state is unknown.
We conducted a telephone survey of patients with obesity. All were seeking weight loss surgery at two bariatric centers (70 % response rate). We assessed patients' health utility (preference-based quality life measure) via a series of standard gamble scenarios assessing patients' willingness to risk death to lose various amounts of weight or achieve perfect health (range 0 to 1; 0 = death and 1 = most valued health/weight state). Multivariable models assessed associations among quality of life domains from the Short-form 36 (SF-36) and Impact of Weight on Quality of Life-lite (IWQOL-lite) and patients' health utility.
Our study sample (n = 574) had a mean body mass index of 46.5 kg/m(2) and a mean health utility of 0.87, reflecting the group's average willingness to accept a 13 % risk of death to achieve their most desired health/weight state; utilities were highly variable, however, with 10 % reporting a utility of 1.00 and 27 % reporting a utility lower than 0.90. Among the IWQOL-lite subscales, Public Distress and Work Life were the only two subscales significantly associated with patients' utility after adjustment for sociodemographic factors. Among the SF-36 subscales, Role Physical, Physical Functioning, and Role Emotional were significantly associated with patients' utility. When the leading subscales on both IWQOL-lite and SF-36 were considered together, Role Physical, Public Distress, and to a lesser degree Role Emotional remained independently associated with patients' health utility.
Patients seeking weight loss surgery report health utilities similar to those reported for people living with diabetes or with laryngeal cancer; however, utility values varied widely with more than a quarter of patients willing to accept more than a 10 % risk of death to achieve their most valued health/weight state. Interference with role functioning due to physical limitations and obesity-related social stigma were strong determinants of reduced health utility.
肥胖是一种带有负面心理社会后果的污名化状况。体重歧视在降低健康效用或个人对当前健康状况的重视程度方面的相对重要性尚不清楚。
我们对肥胖患者进行了电话调查。所有患者均在两家减重中心寻求减重手术(应答率为 70%)。我们通过一系列标准博彩情景评估了患者的健康效用(偏好质量生命测量),评估患者愿意冒险死亡以减轻不同体重或达到完美健康的程度(范围为 0 到 1;0 表示死亡,1 表示最有价值的健康/体重状态)。多变量模型评估了 Short-form 36(SF-36)和 Impact of Weight on Quality of Life-lite(IWQOL-lite)的生活质量领域与患者健康效用之间的关联。
我们的研究样本(n=574)的平均体重指数为 46.5kg/m2,平均健康效用为 0.87,反映出该组平均愿意接受 13%的死亡风险以达到他们最理想的健康/体重状态;然而,效用值变化很大,有 10%的人报告效用值为 1.00,27%的人报告效用值低于 0.90。在 IWQOL-lite 子量表中,公共痛苦和工作生活是调整社会人口因素后与患者效用唯一显著相关的两个子量表。在 SF-36 子量表中,身体角色、身体功能和情绪角色与患者的效用显著相关。当考虑到 IWQOL-lite 和 SF-36 的主要子量表时,身体角色、公共痛苦以及在较小程度上的情绪角色仍然与患者的健康效用独立相关。
寻求减重手术的患者报告的健康效用与糖尿病或喉癌患者报告的健康效用相似;然而,效用值差异很大,超过四分之一的患者愿意接受超过 10%的死亡风险以达到他们最有价值的健康/体重状态。身体功能受限和肥胖相关的社会污名对角色功能的干扰是降低健康效用的重要决定因素。