Nonhuman primate models for HIV cure research.
作者信息
Apetrei Cristian, Pandrea Ivona, Mellors John W
机构信息
Center for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
出版信息
PLoS Pathog. 2012;8(8):e1002892. doi: 10.1371/journal.ppat.1002892. Epub 2012 Aug 30.
Abstract
摘要
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本文引用的文献
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A highly intensified ART regimen induces long-term viral suppression and restriction of the viral reservoir in a simian AIDS model.一种高强度的抗逆转录病毒疗法方案可在猴艾滋病模型中诱导长期病毒抑制和限制病毒储存库。
PLoS Pathog. 2012;8(6):e1002774. doi: 10.1371/journal.ppat.1002774. Epub 2012 Jun 21.
2
PD-1 blockade during chronic SIV infection reduces hyperimmune activation and microbial translocation in rhesus macaques.慢性 SIV 感染期间的 PD-1 阻断可减少恒河猴的过度免疫激活和微生物易位。
J Clin Invest. 2012 May;122(5):1712-6. doi: 10.1172/JCI60612. Epub 2012 Apr 23.
3
HIV prevention by oral preexposure prophylaxis.口腔暴露前预防（PrEP）进行艾滋病预防。
Cold Spring Harb Perspect Med. 2012 Mar;2(3):a007419. doi: 10.1101/cshperspect.a007419.
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New tools for quantifying HIV-1 reservoirs: plasma RNA single copy assays and beyond.用于量化 HIV-1 储存库的新工具：血浆 RNA 单拷贝测定法及其他方法。
Curr HIV/AIDS Rep. 2012 Mar;9(1):91-100. doi: 10.1007/s11904-011-0104-6.
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Facts and fiction: cellular models for high throughput screening for HIV-1 reactivating drugs.事实与虚构：用于高通量筛选HIV-1激活药物的细胞模型
Curr HIV Res. 2011 Dec 1;9(8):568-78. doi: 10.2174/157016211798998826.
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Homeostatic proliferation fails to efficiently reactivate HIV-1 latently infected central memory CD4+ T cells.稳态增殖未能有效重新激活潜伏感染的 HIV-1 中央记忆性 CD4+T 细胞。
PLoS Pathog. 2011 Oct;7(10):e1002288. doi: 10.1371/journal.ppat.1002288. Epub 2011 Oct 6.
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9
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PLoS Pathog. 2011 Aug;7(8):e1002170. doi: 10.1371/journal.ppat.1002170. Epub 2011 Aug 4.
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