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塑料闪烁体在小光子场中的准确性及能谱鉴别方法的实验研究

Experimental investigation on the accuracy of plastic scintillators and of the spectrum discrimination method in small photon fields.

作者信息

Papaconstadopoulos Pavlos, Archambault Louis, Seuntjens Jan

机构信息

McGill University, Medical Physics Unit, Department of Radiation Oncology, SMBD Jewish General Hospital, 3755 Côte-Ste-Catherine Road, Montréal, Québec, H3T 1E2, Canada.

Département de Physique, de Génie Physique et d' Optique, Université Laval, Quèbec, G1K 7P4, Canada.

出版信息

Med Phys. 2017 Feb;44(2):654-664. doi: 10.1002/mp.12064. Epub 2017 Feb 6.

Abstract

PURPOSE

To investigate the accuracy of output factor measurements using a commercial (Exradin W1, SI) and a prototype, "in-house" developed, plastic scintillation dosimeter (PSD) in small photon fields.

METHODS

Repetitive detector-specific output factor OF measurements were performed in water (parallel to the CAX) using two W1 PSDs (SI), a PTW microLion, a PTW microDiamond and an unshielded diode D1V (SI) to which Monte Carlo calculated corrections factors were applied. Four sets of repetitive measurements were performed with the W1 PSD positioned parallel and perpendicular to the CAX, each set on a different day, and with analytically calculated volume averaging corrections applied. The W1 OF measurements were compared to measurements using an "in-house" developed PSD in water (CHUQ) and both were validated against a previously commissioned Monte Carlo beam model in small photon fields. The performance of the spectrum discrimination calibration procedure was evaluated under different fiber orientations and wavelength threshold choices and the impact on the respective OF was reported.

RESULTS

For all detectors in the study an excellent agreement was observed down to a field size of 1 × 1 cm . For the smallest field size of 0.5 × 0.5 cm , the W1 PSDs presented OF readings higher by 3.8 to 5.0% relative to the mean corrected OF of the rest of the detectors and by 5.8 to 6.1% relative to the CHUQ PSD. The repetitive W1 OF measurements in water (parallel CAX) were higher by 3.9% relative to the OF measurements in Solid Water (perpendicular CAX) even after volume averaging corrections were applied, indicating a potential fiber orientation dependency in small fields. Uncertainties in jaw and detector repositioning as well as source variations with time were estimated to be less than 0.9% (1 σ) for the W1 under both orientations. The CHUQ PSD agreed with the MC dose calculations in water, for the smallest field size, within 1.1-1.7% before any corrections and within 0.3-0.8% after volume averaging corrections. The spectrum discrimination method provided reproducible Cherenkov spectra under the different calibration set-ups with noisier spectra extracted if the calibration is performed in water and parallel to the CAX. The impact of fiber orientation and wavelength threshold during calibration on OF was in general minimal.

CONCLUSIONS

Clinically relevant differences were observed between similar scintillator dosimeters in photon fields smaller than 1 ×  1 cm . Further research on PSDs is needed that can explain the origin of these differences especially related to the Cherenkov spectrum dependencies on the optical fiber technical characteristics.

摘要

目的

研究使用商用(Exradin W1,SI)和自行研发的塑料闪烁剂量仪(PSD)原型在小光子场中测量输出因子的准确性。

方法

使用两个W1 PSD(SI)、一个PTW microLion、一个PTW microDiamond和一个未屏蔽二极管D1V(SI)在水中(与中心轴平行)进行特定探测器的重复输出因子OF测量,并应用蒙特卡罗计算的校正因子。将W1 PSD平行和垂直于中心轴放置进行四组重复测量,每组在不同日期进行,并应用解析计算的体积平均校正。将W1的OF测量结果与在水中使用自行研发的PSD(CHUQ)的测量结果进行比较,并在小光子场中根据先前调试的蒙特卡罗束模型对两者进行验证。在不同的光纤取向和波长阈值选择下评估光谱鉴别校准程序的性能,并报告其对各自OF的影响。

结果

对于研究中的所有探测器,在1×1 cm的场大小下都观察到了极好的一致性。对于0.5×0.5 cm的最小场大小,W1 PSD的OF读数相对于其他探测器的平均校正OF高3.8%至5.0%,相对于CHUQ PSD高5.8%至6.1%。即使应用了体积平均校正后,W1在水中(平行于中心轴)的重复OF测量相对于在固体水中(垂直于中心轴)的OF测量仍高3.9%,这表明在小场中可能存在光纤取向依赖性。对于W1,在两种取向情况下,颌骨和探测器重新定位的不确定性以及源随时间的变化估计小于0.9%(1σ)。对于最小场大小,CHUQ PSD在水中与蒙特卡罗剂量计算结果在未进行任何校正前相差1.1% - 1.7%,在进行体积平均校正后相差0.3% - 0.8%。光谱鉴别方法在不同的校准设置下提供了可重复的切伦科夫光谱,如果在校准过程中在水中且与中心轴平行进行,则提取的光谱噪声更大。校准过程中光纤取向和波长阈值对OF的影响通常很小。

结论

在小于1×1 cm的光子场中,类似的闪烁剂量仪之间观察到了临床相关差异。需要对PSD进行进一步研究,以解释这些差异的来源,特别是与切伦科夫光谱对光纤技术特性的依赖性有关的差异。

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