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乌干达东部金贾和伊甘加地区传统治疗师治疗精神病的自然结果 - 3 个月和 6 个月随访。

Naturalistic outcome of treatment of psychosis by traditional healers in Jinja and Iganga districts, Eastern Uganda - a 3- and 6 months follow up.

机构信息

Department of Psychiatry, College of Health Sciences, Makerere University, P,O Box 7072, Kampala, Uganda.

出版信息

Int J Ment Health Syst. 2012 Sep 8;6(1):13. doi: 10.1186/1752-4458-6-13.

Abstract

OBJECTIVE

To determine the naturalistic outcome of treatment of psychosis by traditional healers in Jinja and Iganga districts of Eastern Uganda.

METHOD

A cohort of patients with psychosis receiving treatment from traditional healers' shrines were recruited between January and March 2008 and followed up at three and six months. The Mini International Neuropsychiatry Interview (MINI Plus) was used for making specific diagnosis at the point of contact. For specific symptoms, Positive and Negative Symptom Scale (PANSS), Young Mania Rating Scale (YMRS) and Montgomery Asberg Depression Rating Scale (MADRS) were used to measure severity of schizophrenia, mania and psychotic depression, respectively. The Clinical Global Impression (CGI) and Global Assessment of Functioning (GAF) were used for objective assessments. The Compass Mental Health Index measured well being. Mean scores of the scales were computed using one way ANOVA for independent samples. Associations between outcome and categorical variables were examined at bivariate and multivariate levels.

RESULTS

All the symptom scales had a percentage reduction of more than 20% at three and six months follow up. The differences between the mean scores of the scales at baseline and 3 months, baseline and 6 months, and 3 and 6 months were all significant (P < 0.0001). The post test for pair wise comparisons, the Tukey HSD (Honestly Significant Difference) test was also all significant at P < 0.01 except for MADRS where there was no significant difference between 3 and 6 months for depression severity. Over 80% of the participants used biomedical services for the same symptoms in the study period. At 3 months follow up, patients who combined treatment were less likely to be cases (P = 0.002; OR 0.26 [0.15-0.58]), but more likely to be cases at 6 months follow up (P = 0.020; OR 2.05 [1.10-3.189]). Being in debt was associated with caseness both at 3 and 6 months.

CONCLUSION

This study suggests that there may be some positive effects for patients with psychosis who combine both biomedical services and traditional healing. Further research in the area of naturalistic outcome of traditional healing is necessary.

摘要

目的

在乌干达东部的 Jinja 和 Iganga 地区,确定传统治疗师治疗精神病的自然结果。

方法

2008 年 1 月至 3 月期间,我们招募了一批在传统治疗师圣地接受治疗的精神病患者,并在 3 个月和 6 个月时进行了随访。在接触点使用迷你国际神经精神病学访谈 (MINI Plus) 进行特定诊断。对于特定症状,使用阳性和阴性症状量表 (PANSS)、杨氏躁狂评定量表 (YMRS) 和蒙哥马利抑郁评定量表 (MADRS) 分别测量精神分裂症、躁狂症和精神病性抑郁症的严重程度。使用临床总体印象 (CGI) 和总体功能评估 (GAF) 进行客观评估。罗盘心理健康指数用于衡量幸福感。使用独立样本的单向方差分析计算量表的平均得分。在双变量和多变量水平上检查结局与分类变量之间的关联。

结果

所有症状量表在 3 个月和 6 个月随访时的百分比均下降超过 20%。基线和 3 个月、基线和 6 个月以及 3 个月和 6 个月之间的量表平均得分差异均具有统计学意义 (P < 0.0001)。配对比较的后测,即 Tukey HSD(Honestly Significant Difference)检验在 P < 0.01 时也均具有统计学意义,除 MADRS 外,抑郁严重程度在 3 个月和 6 个月之间无统计学差异。在研究期间,超过 80%的参与者因相同症状同时使用生物医学服务。在 3 个月随访时,同时接受治疗的患者不太可能成为病例 (P = 0.002;OR 0.26 [0.15-0.58]),但在 6 个月随访时更有可能成为病例 (P = 0.020;OR 2.05 [1.10-3.189])。负债与 3 个月和 6 个月时的病例均相关。

结论

这项研究表明,同时接受生物医学服务和传统治疗的精神病患者可能会有一些积极的效果。需要进一步研究传统治疗的自然结果领域。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c101/3533959/d2ea9a33bb37/1752-4458-6-13-1.jpg

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