Garland Eric L
College of Social Work, Trinity Institute for the Addictions, Florida State University, 296 Champions Way, Tallahassee, FL 32306-2570, USA.
Prim Care. 2012 Sep;39(3):561-71. doi: 10.1016/j.pop.2012.06.013. Epub 2012 Jul 24.
This selective review discusses the psychobiological mediation of nociception and pain. Summarizing literature from physiology and neuroscience, first an overview of the neuroanatomic and neurochemical systems underpinning pain perception and modulation is provided. Second, findings from psychological science are used to elucidate cognitive, emotional, and behavioral factors central to the pain experience. This review has implications for clinical practice with patients suffering from chronic pain, and provides strong rationale for assessing and treating pain from a biopsychosocial perspective.
这篇选择性综述讨论了伤害感受和疼痛的心理生物学调节机制。通过总结生理学和神经科学的文献，首先概述了支撑疼痛感知和调节的神经解剖学和神经化学系统。其次，运用心理学的研究结果来阐明疼痛体验中核心的认知、情感和行为因素。这篇综述对慢性疼痛患者的临床实践具有启示意义，并为从生物心理社会角度评估和治疗疼痛提供了有力的理论依据。
