Al-Zamil Mustafa, Minenko Inessa A, Shnayder Natalia A, Petrova Marina M, Babochkina Zarina M, Kaskaeva Darya S, Lim Vladimir G, Khripunova Olga V, Shurygina Irina P, Garganeeva Natalia P
Department of Physiotherapy, Faculty of Continuing Medical Education, Peoples' Friendship University of Russia, 117198 Moscow, Russia.
Department of Restorative Medicine and Neurorehabilitation, Medical Dental Institute, 127253 Moscow, Russia.
J Clin Med. 2025 Jun 14;14(12):4247. doi: 10.3390/jcm14124247.
Previous studies have indicated that transcutaneous electrical nerve stimulation (TENS) is highly effective in improving the treatment of neuropathy and achieving maximum recovery in the shortest time. However, its effectiveness in the early stages of the disease has not been studied, and no comparative analysis has been conducted between different modalities of TENS. This study included 82 patients with acute and subacute fibular tunnel (FT) syndrome lasting no more than 15 days. Patients were randomized into the following four groups depending on the modality of TENS used: sham TENS (20 patients), HF TENS (20 patients), LF TENS (21 patients), and a combined HF/LF TENS group (21 patients). Before treatment, immediately after treatment, and 3 months after the end of treatment patients were examined to determine the severity of hypoesthesia, motor deficit, and gait disturbance. The reduction in hypoesthesia averaged after HF TENS, LF TENS, and sham TENS was 50.7% ( ≤ 0.01), 37.8 ( ≤ 0.01), and 11.4% ( > 0.05), respectively. The regression of motor deficit and gate disorders reached 61% after LF TENS ( ≤ 0.01), 6% after HF TENS ( > 0.05), and 6% ( > 0.05) after sham TENS. The combination of HF and LF TENS resulted in a 54.8% ( ≤ 0.01) reduction in hypoesthesia and 61.3% ( ≤ 0.01) regression of motor deficit, with a superior 30% ( ≤ 0.05) improvement in quality of life compared to separate use of HF and LF TENS. Early use of TENS in the treatment of FT syndrome turned out to be highly effective compared to sham TENS in reducing hypoesthesia, motor deficit, and gait disturbance. The analgesic effect and sensory recovery were higher after HF TENS. Motor and gait disturbances were reduced only after LF TENS, with evidence of prolonged regenerative and protective effect for at least 3 months after the end of treatment. The combination of HF TENS and LF TENS increases the therapeutic range of TENS with the achievement of the maximum positive effect of HF TENS and LF TENS after treatment and during the long-term period, which leads to a more pronounced improvement in the quality of life of patients with this pathology.
先前的研究表明,经皮电神经刺激(TENS)在改善神经病变治疗及在最短时间内实现最大程度恢复方面非常有效。然而,其在疾病早期阶段的有效性尚未得到研究,且未对不同模式的TENS进行比较分析。本研究纳入了82例急性和亚急性腓骨隧道(FT)综合征患者,病程不超过15天。根据所使用的TENS模式,患者被随机分为以下四组:假TENS组(20例患者)、高频TENS组(20例患者)、低频TENS组(21例患者)和高频/低频联合TENS组(21例患者)。在治疗前、治疗结束后即刻以及治疗结束后3个月对患者进行检查,以确定感觉减退、运动功能障碍和步态紊乱的严重程度。高频TENS、低频TENS和假TENS后感觉减退的平均减轻程度分别为50.7%(≤0.01)、37.8%(≤0.01)和11.4%(>0.05)。低频TENS后运动功能障碍和步态紊乱的恢复率达到61%(≤0.01),高频TENS后为6%(>0.05),假TENS后为6%(>0.05)。高频和低频TENS联合使用使感觉减退减轻了54.8%(≤0.01),运动功能障碍恢复了61.3%(≤0.01),与单独使用高频和低频TENS相比,生活质量改善了30%(≤0.05)。与假TENS相比,在FT综合征治疗中早期使用TENS在减轻感觉减退、运动功能障碍和步态紊乱方面非常有效。高频TENS后的镇痛效果和感觉恢复更高。仅低频TENS后运动和步态紊乱有所减轻,治疗结束后至少3个月有再生和保护作用延长的证据。高频TENS和低频TENS联合使用扩大了TENS的治疗范围,在治疗后及长期内实现了高频TENS和低频TENS的最大积极效果,从而使该病症患者的生活质量得到更显著改善。