Bacharach S L, Bonow R O, Green M V
Department of Nuclear Medicine, National Institutes of Health, Bethesda, Maryland 20892.
J Nucl Med. 1990 Jan;31(1):38-42.
In each of 50 resting subjects, two gated blood-pool image sequences were created from the same LIST mode data set. One sequence was created using a sorting method that spans each individual cardiac cycle with the same number of images (the "variable temporal" or VT method), while the other (the "fixed temporal" or FT method) spans the average cardiac cycle with images of fixed temporal duration. Left ventricular time-activity curves were extracted from each sequence using identical regions-of-interest and analyzed with identical methods to obtain estimates of ejection fraction, peak ejection rate, peak filling rate, and the times of occurrence of these peak rates. Differences among certain of these parameters in kind and amount support the hypothesis that estimates of resting cardiac function are more accurately portrayed by the FT method. The magnitudes of these differences are small for systolic parameters but large for early diastolic parameters. Thus, although both methods might be used for measuring systolic function, the FT method will yield a more accurate estimate of peak filling rate in resting subjects.
在50名静息受试者中，从相同的列表模式数据集中创建了两个门控血池图像序列。一个序列是使用一种排序方法创建的，该方法用相同数量的图像跨越每个个体心动周期（“可变时间”或VT方法），而另一个序列（“固定时间”或FT方法）用固定持续时间的图像跨越平均心动周期。使用相同的感兴趣区域从每个序列中提取左心室时间-活动曲线，并使用相同的方法进行分析，以获得射血分数、峰值射血率、峰值充盈率以及这些峰值率出现时间的估计值。这些参数在种类和数量上的差异支持了这样的假设，即FT方法能更准确地描绘静息心功能的估计值。这些差异的幅度对于收缩期参数来说较小，但对于舒张早期参数来说较大。因此，虽然两种方法都可用于测量收缩功能，但FT方法将能更准确地估计静息受试者的峰值充盈率。
