一种用于左心室压力-容积环术后可视化和分析的系统。
A system for postoperative visualization and analysis of left ventricular pressure-volume loops.
作者信息
Beard B B, Stewart J R, Fischell T A
机构信息
Food and Drug Administration, Center for Devices and Radiological Health, Electrophysics Branch, Rockville, MD 20850, USA.
出版信息
Comput Biol Med. 1998 Jan;28(1):1-12. doi: 10.1016/s0010-4825(97)00045-0.
A patient monitoring system for continuous real-time monitoring of left ventricular (LV) function in the postoperative setting was developed. Common hemodynamic parameters and LV functional indices are all calculated from left ventricular pressure-volume loops (PV-loops). Visualization of the PV-loops, along with the hemodynamic parameter derived from them, provides valuable insight into ventricular function and patient recovery. The pressure component is obtained via a pressure sensing catheter placed during surgery. Volume is measured via non-imaging radionuclide techniques using a modified Capintec-VEST. Following surgery and transfer to the recovery unit, the patient's blood is labeled with Tc-99m. A portable gamma camera is used to measure baseline ejection fraction (EF) and to aid in placing the VEST. The specific radioactivity of the blood is calibrated using the baseline EF and thermodilution cardiac output. To confirm the volume measurement accuracy of this technique six patients undergoing bilateral heart catheterization were studied. Single-plane cineventriculographic LV volumes were compared to those calculated from the VEST's time activity curve.
开发了一种用于术后连续实时监测左心室（LV）功能的患者监测系统。常见的血流动力学参数和左心室功能指标均根据左心室压力-容积环（PV环）计算得出。PV环及其衍生的血流动力学参数的可视化，为心室功能和患者恢复提供了有价值的见解。压力分量通过手术期间放置的压力传感导管获得。容积通过使用改良的卡平泰克-VEST的非成像放射性核素技术进行测量。手术后，患者被转移到恢复病房，其血液用Tc-99m标记。使用便携式伽马相机测量基线射血分数（EF）并辅助放置VEST。使用基线EF和热稀释心输出量校准血液的比放射性。为了确认该技术的容积测量准确性，对6例接受双侧心导管检查的患者进行了研究。将单平面电影心室造影的左心室容积与根据VEST的时间-活性曲线计算得出的容积进行比较。
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