Department of Medicine, Saint Peter's University Hospital, 254, Easton avenue, New Brunswick, NJ 08901, USA.
Clin Res Hepatol Gastroenterol. 2013 Apr;37(2):177-81. doi: 10.1016/j.clinre.2012.07.011. Epub 2012 Sep 7.
To evaluate the demographics, risk factors and outcomes of pregnancy associated pancreatitis (PAP).
A retrospective chart review was done using ICD-9 Code 577.0 (acute pancreatitis) from January 2005 through December 2009. Women aged 18 to 45 years, who were pregnant and 6 months after delivery were considered for the study. For each case, two women of the same age (± 4 years) with no history of pancreatitis were matched as control. Demographics, etiology, diagnostic modality and intervention were obtained.
During the 5 years of study, 29 cases of PAP occurred among 25,600 total hospital deliveries, yielding prevalence of 0.001%: Hispanics 48%, Caucasians 24%, African Americans 17.2%, and Asian/Pacific Islanders 13% (P<0.05). Sixty-five percent of those with pre-pregnancy body mass index (BMI) more than 30 kg/m(2) had PAP, versus 24% with BMI between 25 and 30 kg/m(2) and 10% with BMI less than 25 kg/m(2) (P<0.05). An increasing trend of PAP was seen with gestational age and number of pregnancy.
Gallstone disease is the most frequent etiology for PAP and tends to occur more often in Hispanics in New Jersey.
评估妊娠相关性胰腺炎（PAP）的人口统计学、危险因素和结局。
使用 ICD-9 编码 577.0（急性胰腺炎）对 2005 年 1 月至 2009 年 12 月期间的病历进行回顾性图表分析。研究纳入年龄在 18 至 45 岁之间、妊娠且产后 6 个月的女性。对于每例病例，选择两名年龄相同（±4 岁）且无胰腺炎病史的女性作为对照。获取人口统计学、病因、诊断方式和干预措施的数据。
在 5 年的研究期间，25600 例总分娩中有 29 例发生 PAP，患病率为 0.001%：西班牙裔 48%、白种人 24%、非裔美国人 17.2%、亚洲/太平洋岛民 13%（P<0.05）。在患有妊娠前体重指数（BMI）超过 30 kg/m(2)的患者中，有 65%患有 PAP，而 BMI 在 25 至 30 kg/m(2)之间的患者占 24%，BMI 小于 25 kg/m(2)的患者占 10%（P<0.05）。PAP 的发生率随着孕龄和妊娠次数的增加而增加。
胆石病是 PAP 的最常见病因，且在新泽西州的西班牙裔人群中更常见。
