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马来西亚半岛东北部的急性胰腺炎:不寻常的人口统计学和病因模式。

Acute pancreatitis in north-eastern peninsular Malaysia: an unusual demographic and aetiological pattern.

作者信息

Raj S M, Lopez D, Thambidorai C R, Kandasamy P, Toufeeq Khan T F, Mohamad H, Mansur M, Aiyar S

机构信息

School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan.

出版信息

Singapore Med J. 1995 Aug;36(4):371-4.

PMID:8919148
Abstract

A survey of 142 cases of acute pancreatitis was undertaken in two major hospitals serving the state of Kelantan in Malaysia. Females outnumbered males by a ratio of more than 3:1. The incidence among females peaked in the third decade of life. Twenty-one percent (23/109) of the females were pregnant. Ultrasonography revealed gallstones in only 9.4% (13/138). However, abnormalities of serum transaminases were found in 35% (35/100), suggesting that occult gallstones or microlithiasis may be the cause in a significant proportion of patients. Alcohol was virtually absent as an aetiological factor. There was a higher frequency of Ascaris infection in this group than a control hospital population (11/35 vs 33/242; p < 0.02) suggesting that ascariasis may be an important cause of acute pancreatitis in Kelantan. Only 8.4% fell into the category of severe pancreatitis. The overall mortality rate was 2.1%.

摘要

对马来西亚吉兰丹州两家主要医院的142例急性胰腺炎病例进行了调查。女性人数比男性多,比例超过3比1。女性发病率在第三个十年达到峰值。21%(23/109)的女性为孕妇。超声检查仅发现9.4%(13/138)的患者有胆结石。然而,35%(35/100)的患者血清转氨酶异常,提示隐匿性胆结石或微结石可能是相当一部分患者的病因。酒精几乎不是病因。该组蛔虫感染频率高于对照医院人群(11/35对33/242;p<0.02),提示蛔虫病可能是吉兰丹州急性胰腺炎的重要病因。只有8.4%属于重症胰腺炎。总死亡率为2.1%。

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