Raj S M, Lopez D, Thambidorai C R, Kandasamy P, Toufeeq Khan T F, Mohamad H, Mansur M, Aiyar S
School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan.
Singapore Med J. 1995 Aug;36(4):371-4.
A survey of 142 cases of acute pancreatitis was undertaken in two major hospitals serving the state of Kelantan in Malaysia. Females outnumbered males by a ratio of more than 3:1. The incidence among females peaked in the third decade of life. Twenty-one percent (23/109) of the females were pregnant. Ultrasonography revealed gallstones in only 9.4% (13/138). However, abnormalities of serum transaminases were found in 35% (35/100), suggesting that occult gallstones or microlithiasis may be the cause in a significant proportion of patients. Alcohol was virtually absent as an aetiological factor. There was a higher frequency of Ascaris infection in this group than a control hospital population (11/35 vs 33/242; p < 0.02) suggesting that ascariasis may be an important cause of acute pancreatitis in Kelantan. Only 8.4% fell into the category of severe pancreatitis. The overall mortality rate was 2.1%.
对马来西亚吉兰丹州两家主要医院的142例急性胰腺炎病例进行了调查。女性人数比男性多,比例超过3比1。女性发病率在第三个十年达到峰值。21%(23/109)的女性为孕妇。超声检查仅发现9.4%(13/138)的患者有胆结石。然而,35%(35/100)的患者血清转氨酶异常,提示隐匿性胆结石或微结石可能是相当一部分患者的病因。酒精几乎不是病因。该组蛔虫感染频率高于对照医院人群(11/35对33/242;p<0.02),提示蛔虫病可能是吉兰丹州急性胰腺炎的重要病因。只有8.4%属于重症胰腺炎。总死亡率为2.1%。