Gillespie M T, Lyon B R, Skurray R A
Department of Microbiology, Monash University, Clayton, Victoria, Australia.
J Med Microbiol. 1990 Jan;31(1):57-64. doi: 10.1099/00222615-31-1-57.
The identification of new epidemic strains of methicillin-resistant Staphylococcus aureus is essential for rapid, effective infection control. We have developed a typing method which uses antibiotic sensitivity patterns to differentiate methicillin-resistant S. aureus and which is faster and more cost-effective than biochemical analysis or bacteriophage typing. Characterisation of phenotypes which are chromosomally-encoded, plasmid- or chromosomally-encoded or exclusively plasmid-mediated has enabled us to separate Australian strains of methicillin-resistant S. aureus into 11 classes, representatives of which were indistinguishable by bacteriophage type, or plasmid profile alone. The value of this procedure is thus clearly shown.
鉴定耐甲氧西林金黄色葡萄球菌的新流行菌株对于快速、有效地控制感染至关重要。我们开发了一种分型方法，该方法利用抗生素敏感性模式来区分耐甲氧西林金黄色葡萄球菌，并且比生化分析或噬菌体分型更快、更具成本效益。对由染色体编码、质粒或染色体编码或仅由质粒介导的表型进行表征，使我们能够将澳大利亚的耐甲氧西林金黄色葡萄球菌菌株分为11类，仅通过噬菌体类型或质粒图谱无法区分这些类别的代表菌株。因此，该方法的价值得到了明确体现。
