Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Indian J Dermatol Venereol Leprol. 2012 Sep-Oct;78(5):583-90. doi: 10.4103/0378-6323.100556.
Exposure to hair dyes has long been known as a significant risk factor for development of allergic contact dermatitis among the exposed population as these lead to severe eczema of face and upper trunk in the consumer and hand eczema in hair-dressers. Currently, para-phenylenediamine (PPD) is the main ingredient used in permanent hair color products in the market and is the most important allergen. Prevalence of PPD sensitization is high in patients with contact dermatitis across all continents, with hair dye use being the commonest cause. In order to decrease the burden of disease, use of alternative natural dyeing agents among consumers and use of barrier neoprene gloves among hairdressers should be encouraged apart from stringent legislation to reduce the amount of PPD reaching the consumer.
长期以来，人们一直认为接触染发剂是导致暴露人群发生过敏性接触性皮炎的一个重要危险因素，因为这些染发剂会导致消费者面部和上半身出现严重的湿疹，以及美发师手部出现湿疹。目前，对苯二胺（PPD）是市场上永久性染发剂产品中使用的主要成分，也是最重要的过敏原。在所有大陆的接触性皮炎患者中，PPD 致敏的患病率都很高，而染发剂的使用是最常见的原因。为了减轻疾病负担，除了严格的立法以减少消费者接触的 PPD 量外，还应鼓励消费者使用替代天然染料，以及美发师使用防渗透氯丁橡胶手套。
