Department of Occupational and Environmental Dermatology, Skåne University Hospital, Lund University, Jan Waldenströms gata 18, SE 20502, Malmö, Sweden; Department of Biomedical Science and Human Oncology, Unit of Dermatology, University of Bari, Piazza Giulio Cesare, 11, 70124, Bari, Italy.
Contact Dermatitis. 2015 Apr;72(4):229-36. doi: 10.1111/cod.12320. Epub 2014 Nov 19.
The use of permanent hair dyes exposes hairdressers to contact allergens such as p-phenylenediamine (PPD), and the preventive measures are insufficient.
To perform an in vivo test to study the protective effect of gloves commonly used by hairdressers.
PATIENTS/MATERIALS/METHODS: Six gloves from Sweden, Italy and Germany were studied: two vinyl, one natural rubber latex, two nitrile, and one polyethylene. The hair dye used for the provocation was a dark shade permanent dye containing PPD. The dye was mixed with hydrogen peroxide, and 8 PPD-sensitized volunteers were tested with the gloves as a membrane between the hair dye and the skin in a cylindrical open chamber system. Three exposure times (15, 30 and 60 min) were used.
Eczematous reactions were found when natural rubber latex, polyethylene and vinyl gloves were tested with the dye. The nitrile gloves gave good protection, even after 60 min of exposure to the hair dye.
Many protective gloves used by hairdressers are unsuitable for protection against the risk of elicitation of allergic contact dermatitis caused by PPD.
美发师在使用永久性染发剂时会接触到对苯二胺(PPD)等接触性过敏原,而预防措施不足。
进行体内试验以研究美发师常用手套的防护作用。
患者/材料/方法:研究了来自瑞典、意大利和德国的 6 种手套:两种乙烯基手套、一种天然橡胶乳胶手套、两种丁腈手套和一种聚乙烯手套。用于引发的染发剂是一种含有 PPD 的深色永久性染发剂。将染料与过氧化氢混合,然后将 8 名 PPD 致敏志愿者使用这些手套在圆柱形开放式腔系统中作为染料和皮肤之间的膜进行测试。使用了三种暴露时间(15、30 和 60 分钟)。
当用染料测试天然橡胶乳胶、聚乙烯和乙烯基手套时,发现了湿疹反应。丁腈手套提供了良好的保护,即使在暴露于染发剂 60 分钟后也是如此。
许多美发师使用的防护手套不适合防止由 PPD 引起的变应性接触性皮炎的发生。