Unit of Health-Care Epidemiology, Department of Public Health, University of Oxford, Old Road Campus, Oxford OX3 7LF, UK.
J Public Health (Oxf). 2013 Jun;35(2):293-7. doi: 10.1093/pubmed/fds074. Epub 2012 Sep 7.
Most cases of Type 2 diabetes are attributable to excess weight and physical inactivity. We investigated trends in mortality based on doctors' certification of diabetes and obesity.
Analysis of a national data set of all certified causes of death, i.e. underlying cause and contributing causes ('mentions'), in England 1995-2010.
Diabetes exhibited divergent trends for mortality based on underlying cause and mentions. Underlying cause rates were 107.2 per million population [95% confidence interval (CI): 105.7-108.6] in 1995, but only 68.9/10(6) (CI: 67.9-69.9) in 2010. Mortality rates for mentions of diabetes were 403.1/10(6) (CI: 400.4-405.8) in 1995, increasing to 478.4/10(6) (CI: 475.7-481.0) in 2010. Underlying cause mortality for obesity was 3.7/10(6) (CI: 3.2-4.1) in 1995 and 7.5 (CI: 7.0-8.0) in 2010. The corresponding rates for mentions of obesity were 13.2/10(6) (CI: 12.6-13.9) and 34.5/10(6) (CI: 33.6-35.4), respectively. 24.0% of death certificates with a mention of obesity also had diabetes recorded on the same certificate.
Multiple-cause mortality statistics provide a more accurate picture than underlying cause of the total mortality burden attributed on death certificates to diabetes and obesity. Rates for both increased substantially: analysis by underlying cause alone would have missed this for diabetes.
大多数 2 型糖尿病病例可归因于超重和缺乏身体活动。我们调查了基于医生对糖尿病和肥胖的认证的死亡率趋势。
对英格兰 1995-2010 年所有经认证的死因(即根本原因和促成原因[“提及”])的全国数据集进行分析。
糖尿病的死亡率基于根本原因和提及呈现出不同的趋势。1995 年,根本死因率为每百万人 107.2 例(95%置信区间[CI]:105.7-108.6),但 2010 年仅为 68.9/10(6)(CI:67.9-69.9)。1995 年,提及糖尿病的死亡率为每百万人 403.1/10(6)(CI:400.4-405.8),2010 年增至 478.4/10(6)(CI:475.7-481.0)。1995 年,肥胖的根本死因死亡率为每百万人 3.7/10(6)(CI:3.2-4.1),2010 年为每百万人 7.5(CI:7.0-8.0)。肥胖提及的相应死亡率为每百万人 13.2/10(6)(CI:12.6-13.9)和 34.5/10(6)(CI:33.6-35.4)。在有肥胖提及的死亡证明中,有 24.0%的证明上同时记录了糖尿病。
与根本死因相比,多死因死亡率统计数据提供了更准确的糖尿病和肥胖症在死亡证明上归因的总死亡负担的全貌。这两个比率都大幅增加:仅通过根本原因进行分析,就会忽略糖尿病的这种情况。