因静脉注射漂白剂导致的急性肾损伤。
Acute kidney injury due to intravenous bleach injection.
机构信息
Division of Renal Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA.
出版信息
J Med Toxicol. 2013 Mar;9(1):71-4. doi: 10.1007/s13181-012-0259-6.
INTRODUCTION
Sodium hypochlorite is the active ingredient in bleach, a ubiquitous household disinfectant, and has known toxicities depending on route of exposure and amount. Acute kidney injury due to sodium hypochlorite exposure has never been reported. Patients that did develop nephrotoxicity following bleach exposure did so due to development of other risk factors for kidney injury such as volume depletion or sepsis.
DISCUSSION
We report a patient who presented with black urine after parenteral self-administration of a large quantity of bleach. We review the clinical presentation, laboratory and biopsy findings, and outcome as well as discuss possible mechanisms of sodium hypochlorite toxicity and management strategies.
简介
次氯酸钠是漂白剂中的有效成分，漂白剂是一种无处不在的家用消毒剂，其毒性取决于接触途径和剂量。因接触次氯酸钠而导致的急性肾损伤从未有过报道。在接触漂白剂后出现肾毒性的患者，是由于发生了其他导致肾损伤的危险因素，如血容量不足或败血症。
讨论
我们报告了一例患者，因自行大量静脉输注漂白剂后出现黑尿而就诊。我们回顾了其临床表现、实验室和活检结果以及转归，并讨论了次氯酸钠毒性的可能机制和治疗策略。
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