Rosenthal V V, Serikov V B, Belyakov N A, Symbirtsev S A
Kirov Medical Institute, Leningrad, USSR.
J Biomed Eng. 1990 Jan;12(1):46-50. doi: 10.1016/0141-5425(90)90114-3.
We propose a mathematical model of dynamic lung transvascular fluid flow based on linear non-equilibrium thermodynamic equations. The model makes use of experimental results concerning lung fluid balance during hydrodynamic and hypooncotic loading. An 'inexact problem' solution method was employed to solve the mathematical problem and to obtain coefficients of mass transfer. Transport features dependent on the system's condition and on boundary phase surface phenomena were also considered. A complex analysis of such a multi-unit system as the lung is useful for the evaluation of fluid balance mechanisms and their application to the development of artificial mass exchange devices.
我们基于线性非平衡热力学方程提出了一个动态肺血管内液体流动的数学模型。该模型利用了关于流体动力学和低渗负荷期间肺液体平衡的实验结果。采用“不精确问题”求解方法来解决数学问题并获得传质系数。还考虑了取决于系统条件和边界相表面现象的传输特征。对肺这样的多单元系统进行复杂分析，有助于评估液体平衡机制及其在人工质量交换装置开发中的应用。
